1xu6: Difference between revisions
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==Structure of the C-terminal domain from Trypanosoma brucei Variant Surface Glycoprotein MITat1.2== | ==Structure of the C-terminal domain from Trypanosoma brucei Variant Surface Glycoprotein MITat1.2== | ||
<StructureSection load='1xu6' size='340' side='right'caption='[[1xu6 | <StructureSection load='1xu6' size='340' side='right'caption='[[1xu6]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1xu6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[1xu6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_brucei_brucei Trypanosoma brucei brucei]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XU6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XU6 FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xu6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xu6 OCA], [https://pdbe.org/1xu6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xu6 RCSB], [https://www.ebi.ac.uk/pdbsum/1xu6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xu6 ProSAT]</span></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xu6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xu6 OCA], [https://pdbe.org/1xu6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xu6 RCSB], [https://www.ebi.ac.uk/pdbsum/1xu6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xu6 ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/VSM2_TRYBB VSM2_TRYBB] VSG forms a coat on the surface of the parasite. The trypanosome evades the immune response of the host by expressing a series of antigenically distinct VSGs from an estimated 1000 VSG genes. | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: | [[Category: Trypanosoma brucei brucei]] | ||
[[Category: Carrington | [[Category: Carrington M]] | ||
[[Category: Chattopadhyay | [[Category: Chattopadhyay A]] | ||
[[Category: Jones | [[Category: Jones NG]] | ||
[[Category: Mott | [[Category: Mott HR]] | ||
[[Category: Nielsen | [[Category: Nielsen PR]] | ||
[[Category: Nietlispach | [[Category: Nietlispach D]] | ||
[[Category: Voorheis | [[Category: Voorheis HP]] | ||