2ly9: Difference between revisions

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2ly9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LY9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LY9 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2ly9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LY9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LY9 FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ly9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ly9 OCA], [https://pdbe.org/2ly9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ly9 RCSB], [https://www.ebi.ac.uk/pdbsum/2ly9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ly9 ProSAT]</span></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ly9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ly9 OCA], [https://pdbe.org/2ly9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ly9 RCSB], [https://www.ebi.ac.uk/pdbsum/2ly9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ly9 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==

Latest revision as of 08:55, 15 May 2024

Solution NMR Structure of Homeobox 2 Domain from Human ZHX1 repressor, Northeast Structural Genomics Consortium (NESG) Target HR7907FSolution NMR Structure of Homeobox 2 Domain from Human ZHX1 repressor, Northeast Structural Genomics Consortium (NESG) Target HR7907F

Structural highlights

2ly9 is a 1 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Solution NMR
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

ZHX1_HUMAN Acts as a transcriptional repressor. Increases DNMT3B-mediated repressive transcriptional activity when DNMT3B is tethered to DNA. May link molecule between DNMT3B and other co-repressor proteins.[1]

References

  1. ↑ Yamada K, Kawata H, Matsuura K, Shou Z, Hirano S, Mizutani T, Yazawa T, Yoshino M, Sekiguchi T, Kajitani T, Miyamoto K. Functional analysis and the molecular dissection of zinc-fingers and homeoboxes 1 (ZHX1). Biochem Biophys Res Commun. 2002 Sep 20;297(2):368-74. PMID:12237128
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