1x6a: Difference between revisions
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==Solution structures of the second LIM domain of human LIM-kinase 2 (LIMK2)== | ==Solution structures of the second LIM domain of human LIM-kinase 2 (LIMK2)== | ||
<StructureSection load='1x6a' size='340' side='right'caption='[[1x6a | <StructureSection load='1x6a' size='340' side='right'caption='[[1x6a]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1x6a]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[1x6a]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1X6A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1X6A FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1x6a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1x6a OCA], [https://pdbe.org/1x6a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1x6a RCSB], [https://www.ebi.ac.uk/pdbsum/1x6a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1x6a ProSAT], [https://www.topsan.org/Proteins/RSGI/1x6a TOPSAN]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1x6a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1x6a OCA], [https://pdbe.org/1x6a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1x6a RCSB], [https://www.ebi.ac.uk/pdbsum/1x6a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1x6a ProSAT], [https://www.topsan.org/Proteins/RSGI/1x6a TOPSAN]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/LIMK2_HUMAN LIMK2_HUMAN] Displays serine/threonine-specific phosphorylation of myelin basic protein and histone (MBP) in vitro.<ref>PMID:10436159</ref> <ref>PMID:11018042</ref> | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Inoue | [[Category: Inoue M]] | ||
[[Category: Kigawa | [[Category: Kigawa T]] | ||
[[Category: Koshiba | [[Category: Koshiba S]] | ||
[[Category: Nameki | [[Category: Nameki N]] | ||
[[Category: Sasagawa A]] | |||
[[Category: Sasagawa | [[Category: Tomizawa T]] | ||
[[Category: Tomizawa | [[Category: Yokoyama S]] | ||
[[Category: Yokoyama | |||