4uct: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4uct]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Haemophilus_influenzae Haemophilus influenzae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UCT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4UCT FirstGlance]. <br> | <table><tr><td colspan='2'>[[4uct]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Haemophilus_influenzae Haemophilus influenzae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UCT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4UCT FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5U1:2-AMINO-6-METHYL-5-(PROPAN-2-YLOXY)-3H-[1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-8-IUM'>5U1</scene>, <scene name='pdbligand=IWH:1-(2,4-DIMETHYLBENZYL)-6-OXO-1,6-DIHYDROPYRIDINE-3-CARBOXAMIDE'>IWH</scene></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5U1:2-AMINO-6-METHYL-5-(PROPAN-2-YLOXY)-3H-[1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-8-IUM'>5U1</scene>, <scene name='pdbligand=IWH:1-(2,4-DIMETHYLBENZYL)-6-OXO-1,6-DIHYDROPYRIDINE-3-CARBOXAMIDE'>IWH</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4uct FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uct OCA], [https://pdbe.org/4uct PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4uct RCSB], [https://www.ebi.ac.uk/pdbsum/4uct PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4uct ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4uct FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uct OCA], [https://pdbe.org/4uct PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4uct RCSB], [https://www.ebi.ac.uk/pdbsum/4uct PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4uct ProSAT]</span></td></tr> | ||
</table> | </table> | ||
Latest revision as of 14:19, 9 May 2024
Fragment bound to H.influenza NAD dependent DNA ligaseFragment bound to H.influenza NAD dependent DNA ligase
Structural highlights
FunctionDNLJ_HAEIN DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity). See Also |
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