2bll: Difference between revisions

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<StructureSection load='2bll' size='340' side='right'caption='[[2bll]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
<StructureSection load='2bll' size='340' side='right'caption='[[2bll]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2bll]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BLL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BLL FirstGlance]. <br>
<table><tr><td colspan='2'>[[2bll]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BLL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BLL FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1u9j|1u9j]]</div></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/UDP-glucuronate_decarboxylase UDP-glucuronate decarboxylase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.35 4.1.1.35] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2bll FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bll OCA], [https://pdbe.org/2bll PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2bll RCSB], [https://www.ebi.ac.uk/pdbsum/2bll PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2bll ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2bll FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bll OCA], [https://pdbe.org/2bll PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2bll RCSB], [https://www.ebi.ac.uk/pdbsum/2bll PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2bll ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ARNA_ECOLI ARNA_ECOLI] Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.<ref>PMID:11706007</ref> <ref>PMID:15695810</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bacillus coli migula 1895]]
[[Category: Escherichia coli]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: UDP-glucuronate decarboxylase]]
[[Category: Breazeale SD]]
[[Category: Breazeale, S D]]
[[Category: Naismith JH]]
[[Category: Naismith, J H]]
[[Category: Raetz CRH]]
[[Category: Raetz, C R.H]]
[[Category: Williams GJ]]
[[Category: Williams, G J]]
[[Category: Decarboxylase]]
[[Category: L-ara4n biosynthesis]]
[[Category: Methyltransferase]]
[[Category: Short chain dehydrogenase]]
[[Category: Transferase]]

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