1us0: Difference between revisions

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<StructureSection load='1us0' size='340' side='right'caption='[[1us0]], [[Resolution|resolution]] 0.66&Aring;' scene=''>
<StructureSection load='1us0' size='340' side='right'caption='[[1us0]], [[Resolution|resolution]] 0.66&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1us0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1US0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1US0 FirstGlance]. <br>
<table><tr><td colspan='2'>[[1us0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1US0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1US0 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=LDT:IDD594'>LDT</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 0.66&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1abn|1abn]], [[1ads|1ads]], [[1az1|1az1]], [[1az2|1az2]], [[1ef3|1ef3]], [[1el3|1el3]], [[1iei|1iei]], [[1mar|1mar]], [[2acq|2acq]], [[2acr|2acr]], [[2acs|2acs]], [[2acu|2acu]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=LDT:IDD594'>LDT</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Aldehyde_reductase Aldehyde reductase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.21 1.1.1.21] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1us0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1us0 OCA], [https://pdbe.org/1us0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1us0 RCSB], [https://www.ebi.ac.uk/pdbsum/1us0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1us0 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1us0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1us0 OCA], [https://pdbe.org/1us0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1us0 RCSB], [https://www.ebi.ac.uk/pdbsum/1us0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1us0 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/ALDR_HUMAN ALDR_HUMAN]] Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies.  
[https://www.uniprot.org/uniprot/ALDR_HUMAN ALDR_HUMAN] Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Aldehyde reductase]]
[[Category: Homo sapiens]]
[[Category: Human]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Barth, P]]
[[Category: Barth P]]
[[Category: Bon, C]]
[[Category: Bon C]]
[[Category: Cachau, R E]]
[[Category: Cachau RE]]
[[Category: Chevrier, B]]
[[Category: Chevrier B]]
[[Category: Howard, E I]]
[[Category: Howard EI]]
[[Category: Joachimiak, A]]
[[Category: Joachimiak A]]
[[Category: Lamour, V]]
[[Category: Lamour V]]
[[Category: Mitschler, A]]
[[Category: Mitschler A]]
[[Category: Moras, D]]
[[Category: Moras D]]
[[Category: Podjarny, A]]
[[Category: Podjarny A]]
[[Category: Sanishvili, R]]
[[Category: Sanishvili R]]
[[Category: Schneider, T R]]
[[Category: Schneider TR]]
[[Category: Sibley, E]]
[[Category: Sibley E]]
[[Category: Zandt, M Van]]
[[Category: Van Zandt M]]
[[Category: Idd594]]
[[Category: Nadp]]
[[Category: Oxidoreductase]]

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