8owp: Difference between revisions

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-'''Unreleased structure'''
-The entry 8owp is ON HOLD  until Paper Publication
+==Crystal structure of Mycobacterium smegmatis CoaB in complex with CTP and 2-(1-(4-hydroxyphenyl)-5-phenyl-1H-indol-3-yl)-2-oxoacetic acid==
+<StructureSection load='8owp' size='340' side='right'caption='[[8owp]], [[Resolution|resolution]] 1.99&Aring;' scene=''>
-Authors: Mendes, V., Blundell, T.L.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[8owp]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycolicibacterium_smegmatis_MC2_155 Mycolicibacterium smegmatis MC2 155]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8OWP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8OWP FirstGlance]. <br>
-Description: Crystal structure of Mycobacterium smegmatis CoaB in complex with CTP and 2-(1-(4-hydroxyphenyl)-5-phenyl-1H-indol-3-yl)-2-oxoacetic acid
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.993&#8491;</td></tr>
-[[Category: Unreleased Structures]]
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CTP:CYTIDINE-5-TRIPHOSPHATE'>CTP</scene>, <scene name='pdbligand=W52:2-[1-(4-hydroxyphenyl)-5-phenyl-indol-3-yl]-2-oxidanylidene-ethanoic+acid'>W52</scene></td></tr>
-[[Category: Blundell, T.L]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8owp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8owp OCA], [https://pdbe.org/8owp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8owp RCSB], [https://www.ebi.ac.uk/pdbsum/8owp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8owp ProSAT]</span></td></tr>
-[[Category: Mendes, V]]
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/COABC_MYCS2 COABC_MYCS2] Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.[HAMAP-Rule:MF_02225]
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
+[[Category: Mycolicibacterium smegmatis MC2 155]]
+[[Category: Blundell TL]]
+[[Category: Mendes V]]