1sp3: Difference between revisions

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<StructureSection load='1sp3' size='340' side='right'caption='[[1sp3]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
<StructureSection load='1sp3' size='340' side='right'caption='[[1sp3]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1sp3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Sheon Sheon]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SP3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1SP3 FirstGlance]. <br>
<table><tr><td colspan='2'>[[1sp3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Shewanella_oneidensis_MR-1 Shewanella oneidensis MR-1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SP3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1SP3 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEC:HEME+C'>HEC</scene>, <scene name='pdbligand=SCN:THIOCYANATE+ION'>SCN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SO4144 (tigr locus) ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=211586 SHEON])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEC:HEME+C'>HEC</scene>, <scene name='pdbligand=SCN:THIOCYANATE+ION'>SCN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1sp3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sp3 OCA], [https://pdbe.org/1sp3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1sp3 RCSB], [https://www.ebi.ac.uk/pdbsum/1sp3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1sp3 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1sp3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sp3 OCA], [https://pdbe.org/1sp3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1sp3 RCSB], [https://www.ebi.ac.uk/pdbsum/1sp3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1sp3 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q8E9W8_SHEON Q8E9W8_SHEON]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1sp3 ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1sp3 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
We have isolated a soluble cytochrome from Shewanella oneidensis that contains eight covalently attached heme groups and determined its crystal structure. One of these hemes exhibits novel ligation of the iron atom by the epsilon-amino group of a lysine residue, despite its attachment via a typical CXXCH motif. This heme is most likely the active site for tetrathionate reduction, a reaction catalyzed efficiently by this enzyme.
Octaheme tetrathionate reductase is a respiratory enzyme with novel heme ligation.,Mowat CG, Rothery E, Miles CS, McIver L, Doherty MK, Drewette K, Taylor P, Walkinshaw MD, Chapman SK, Reid GA Nat Struct Mol Biol. 2004 Oct;11(10):1023-4. Epub 2004 Sep 7. PMID:15361860<ref>PMID:15361860</ref>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
<div class="pdbe-citations 1sp3" style="background-color:#fffaf0;"></div>
== References ==
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Sheon]]
[[Category: Shewanella oneidensis MR-1]]
[[Category: Chapman, S K]]
[[Category: Chapman SK]]
[[Category: Doherty, M K]]
[[Category: Doherty MK]]
[[Category: Drewette, K]]
[[Category: Drewette K]]
[[Category: McIver, L]]
[[Category: McIver L]]
[[Category: Miles, C S]]
[[Category: Miles CS]]
[[Category: Mowat, C G]]
[[Category: Mowat CG]]
[[Category: Reid, G A]]
[[Category: Reid GA]]
[[Category: Rothery, E]]
[[Category: Rothery E]]
[[Category: Taylor, P]]
[[Category: Taylor P]]
[[Category: Walkinshaw, M D]]
[[Category: Walkinshaw MD]]
[[Category: Cytochrome c]]
[[Category: Octaheme]]
[[Category: Oxidoreductase]]

Revision as of 11:33, 1 May 2024

Crystal structure of octaheme cytochrome c from Shewanella oneidensisCrystal structure of octaheme cytochrome c from Shewanella oneidensis

Structural highlights

1sp3 is a 1 chain structure with sequence from Shewanella oneidensis MR-1. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.2Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

Q8E9W8_SHEON

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

1sp3, resolution 2.20Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA
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