8sfc: Difference between revisions

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'''Unreleased structure'''


The entry 8sfc is ON HOLD  until Paper Publication
==Crystal structure of the engineered SsoPox variant IVA4 in alternate state==
 
<StructureSection load='8sfc' size='340' side='right'caption='[[8sfc]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
Authors: Jacquet, P., Billot, R., Shimon, A., Hoekstra, N., Bergonzi, C., Jenks, A., Daude, D., Elias, M.H.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[8sfc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharolobus_solfataricus_P2 Saccharolobus solfataricus P2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8SFC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8SFC FirstGlance]. <br>
Description: Crystal structure of the engineered SsoPox variant IVA4 in alternate state
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.4&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=KCX:LYSINE+NZ-CARBOXYLIC+ACID'>KCX</scene></td></tr>
[[Category: Hoekstra, N]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8sfc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8sfc OCA], [https://pdbe.org/8sfc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8sfc RCSB], [https://www.ebi.ac.uk/pdbsum/8sfc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8sfc ProSAT]</span></td></tr>
[[Category: Jenks, A]]
</table>
[[Category: Bergonzi, C]]
== Function ==
[[Category: Billot, R]]
[https://www.uniprot.org/uniprot/PHP_SACS2 PHP_SACS2] Has a low paraoxonase activity. Also active, but with a lower activity, against other organo-phosphorus insecticides such as Dursban, Coumaphos, pNP-butanoate or parathion.<ref>PMID:15909078</ref>
[[Category: Jacquet, P]]
== References ==
[[Category: Elias, M.H]]
<references/>
[[Category: Daude, D]]
__TOC__
[[Category: Shimon, A]]
</StructureSection>
[[Category: Large Structures]]
[[Category: Saccharolobus solfataricus P2]]
[[Category: Bergonzi C]]
[[Category: Billot R]]
[[Category: Daude D]]
[[Category: Elias MH]]
[[Category: Hoekstra N]]
[[Category: Jacquet P]]
[[Category: Jenks A]]
[[Category: Shimon A]]

Revision as of 08:29, 17 April 2024

Crystal structure of the engineered SsoPox variant IVA4 in alternate stateCrystal structure of the engineered SsoPox variant IVA4 in alternate state

Structural highlights

8sfc is a 1 chain structure with sequence from Saccharolobus solfataricus P2. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.4Å
Ligands:, , ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

PHP_SACS2 Has a low paraoxonase activity. Also active, but with a lower activity, against other organo-phosphorus insecticides such as Dursban, Coumaphos, pNP-butanoate or parathion.[1]

References

  1. Merone L, Mandrich L, Rossi M, Manco G. A thermostable phosphotriesterase from the archaeon Sulfolobus solfataricus: cloning, overexpression and properties. Extremophiles. 2005 Aug;9(4):297-305. Epub 2005 May 21. PMID:15909078 doi:10.1007/s00792-005-0445-4

8sfc, resolution 1.40Å

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OCA