Sandbox Ben Whiteside: Difference between revisions

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<scene name='10/1038828/Ramp_ctr_interface/5'>RAMP CTR Interface </scene>
<scene name='10/1038828/Ramp_ctr_interface/5'>RAMP CTR Interface </scene>
==== Extracellular Domain - RAMP interactions ====
==== Extracellular Domain - RAMP interactions ====
<scene name='10/1038828/Ctr_ramp_ecd_stablization/4'>RAMP CTR Extracellular Domain Interaction</scene>
<scene name='10/1038828/Ctr_ramp_ecd_stablization/6'>RAMP CTR Extracellular Domain Interaction</scene>
=== Bypass Motif ===
=== Bypass Motif ===
=== G-alpha Interactions with CTR TMD ===
=== G-alpha Interactions with CTR TMD ===

Revision as of 16:58, 11 April 2024

AMYRAMYR

This is a default text for your page Ben Whiteside. Click above on edit this page to modify. Be careful with the < and > signs.

You may include any references to papers as in: the use of JSmol in Proteopedia [1] or to the article describing Jmol [2] to the rescue.

Introduction

Figure 1: AMYR

[3]

[4]

Amylin Peptide

Structure

Transmembrane Domain

N Terminal Disulfide

Receptor Activity Modifying Proteins

Extracellular Domain - RAMP interactions

Bypass Motif

G-alpha Interactions with CTR TMD

Function

Relevance

AMYR Bound to Amylin

Drag the structure with the mouse to rotate

ReferencesReferences

  1. Hanson, R. M., Prilusky, J., Renjian, Z., Nakane, T. and Sussman, J. L. (2013), JSmol and the Next-Generation Web-Based Representation of 3D Molecular Structure as Applied to Proteopedia. Isr. J. Chem., 53:207-216. doi:http://dx.doi.org/10.1002/ijch.201300024
  2. Herraez A. Biomolecules in the computer: Jmol to the rescue. Biochem Mol Biol Educ. 2006 Jul;34(4):255-61. doi: 10.1002/bmb.2006.494034042644. PMID:21638687 doi:10.1002/bmb.2006.494034042644
  3. Ransey E, Paredes E, Dey SK, Das SR, Heroux A, Macbeth MR. Crystal structure of the Entamoeba histolytica RNA lariat debranching enzyme EhDbr1 reveals a catalytic Zn(2+) /Mn(2+) heterobinucleation. FEBS Lett. 2017 Jul;591(13):2003-2010. doi: 10.1002/1873-3468.12677. Epub 2017, Jun 14. PMID:28504306 doi:http://dx.doi.org/10.1002/1873-3468.12677
  4. Cao J, Belousoff MJ, Liang YL, Johnson RM, Josephs TM, Fletcher MM, Christopoulos A, Hay DL, Danev R, Wootten D, Sexton PM. A structural basis for amylin receptor phenotype. Science. 2022 Mar 25;375(6587):eabm9609. PMID:35324283 doi:10.1126/science.abm9609


Student ContributorsStudent Contributors

Ben Whiteside, Mathias Vander Eide, Andrew Helmerich,

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Ben Whiteside, Andrew Helmerich, Mathias Vander Eide, Wayne Decatur