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==== | ==Crystal structure of Fab239 in complex with NPNA4 peptide from circumsporozoite protein== | ||
<StructureSection load='6wg2' size='340' side='right'caption='[[6wg2]]' scene=''> | <StructureSection load='6wg2' size='340' side='right'caption='[[6wg2]], [[Resolution|resolution]] 2.53Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br> | <table><tr><td colspan='2'>[[6wg2]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6WG2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6WG2 FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6wg2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6wg2 OCA], [https://pdbe.org/6wg2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6wg2 RCSB], [https://www.ebi.ac.uk/pdbsum/6wg2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6wg2 ProSAT]</span></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.534Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6wg2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6wg2 OCA], [https://pdbe.org/6wg2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6wg2 RCSB], [https://www.ebi.ac.uk/pdbsum/6wg2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6wg2 ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/CSP_PLAFA CSP_PLAFA] The circumsporozoite protein is the immunodominant surface antigen on the sporozoite (the infective stage of the malaria parasite that is transmitted from the mosquito to the vertebrate host). | |||
==See Also== | |||
*[[Monoclonal Antibodies 3D structures|Monoclonal Antibodies 3D structures]] | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: | [[Category: Plasmodium falciparum]] | ||
[[Category: Oyen D]] | |||
[[Category: Pholcharee T]] | |||
[[Category: Wilson IA]] | |||
Revision as of 10:10, 3 April 2024
Crystal structure of Fab239 in complex with NPNA4 peptide from circumsporozoite proteinCrystal structure of Fab239 in complex with NPNA4 peptide from circumsporozoite protein
Structural highlights
FunctionCSP_PLAFA The circumsporozoite protein is the immunodominant surface antigen on the sporozoite (the infective stage of the malaria parasite that is transmitted from the mosquito to the vertebrate host). See Also |
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