7btw: Difference between revisions

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====
==The mitochondrial SAM complex from S.cere==
<StructureSection load='7btw' size='340' side='right'caption='[[7btw]]' scene=''>
<StructureSection load='7btw' size='340' side='right'caption='[[7btw]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>
<table><tr><td colspan='2'>[[7btw]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7BTW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7BTW FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7btw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7btw OCA], [https://pdbe.org/7btw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7btw RCSB], [https://www.ebi.ac.uk/pdbsum/7btw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7btw ProSAT]</span></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7btw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7btw OCA], [https://pdbe.org/7btw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7btw RCSB], [https://www.ebi.ac.uk/pdbsum/7btw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7btw ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SAM35_YEAST SAM35_YEAST] Essential component of the mitochondrial outer membrane sorting assembly machinery (SAM or TOB) complex, which is required for the sorting of proteins with complicated topology, such as beta-barrel proteins, to the mitochondrial outer membrane after import by the TOM complex.<ref>PMID:14699090</ref> <ref>PMID:15067005</ref>
== References ==
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Z-disk]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Endo T]]
[[Category: Kikkawa M]]
[[Category: Nishizawa T]]
[[Category: Nureki O]]
[[Category: Takeda H]]
[[Category: Tsutsumi A]]

Latest revision as of 13:49, 27 March 2024

The mitochondrial SAM complex from S.cereThe mitochondrial SAM complex from S.cere

Structural highlights

7btw is a 4 chain structure with sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Electron Microscopy, Resolution 2.9Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

SAM35_YEAST Essential component of the mitochondrial outer membrane sorting assembly machinery (SAM or TOB) complex, which is required for the sorting of proteins with complicated topology, such as beta-barrel proteins, to the mitochondrial outer membrane after import by the TOM complex.[1] [2]

References

  1. Gentle I, Gabriel K, Beech P, Waller R, Lithgow T. The Omp85 family of proteins is essential for outer membrane biogenesis in mitochondria and bacteria. J Cell Biol. 2004 Jan 5;164(1):19-24. PMID:14699090 doi:10.1083/jcb.200310092
  2. Milenkovic D, Kozjak V, Wiedemann N, Lohaus C, Meyer HE, Guiard B, Pfanner N, Meisinger C. Sam35 of the mitochondrial protein sorting and assembly machinery is a peripheral outer membrane protein essential for cell viability. J Biol Chem. 2004 May 21;279(21):22781-5. PMID:15067005 doi:10.1074/jbc.C400120200

7btw, resolution 2.90Å

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