3fxj: Difference between revisions

<table><tr><td colspan='2'>[[3fxj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FXJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3FXJ FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>

<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3fxj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fxj OCA], [https://pdbe.org/3fxj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3fxj RCSB], [https://www.ebi.ac.uk/pdbsum/3fxj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3fxj ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/PPM1A_HUMAN PPM1A_HUMAN] Enzyme with a broad specificity. Negatively regulates TGF-beta signaling through dephosphorylating SMAD2 and SMAD3, resulting in their dissociation from SMAD4, nuclear export of the SMADs and termination of the TGF-beta-mediated signaling.<ref>PMID:16751101</ref>  

[[Category: Homo sapiens]]

[[Category: Hu T]]

[[Category: Jiang H]]

[[Category: Shen X]]

[[Category: Wang K]]

[[Category: Wang L]]