3tg7: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3tg7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_adenovirus_5 Human adenovirus 5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TG7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TG7 FirstGlance]. <br> | <table><tr><td colspan='2'>[[3tg7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_adenovirus_5 Human adenovirus 5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TG7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TG7 FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tg7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tg7 OCA], [https://pdbe.org/3tg7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tg7 RCSB], [https://www.ebi.ac.uk/pdbsum/3tg7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tg7 ProSAT]</span></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.57Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tg7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tg7 OCA], [https://pdbe.org/3tg7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tg7 RCSB], [https://www.ebi.ac.uk/pdbsum/3tg7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tg7 ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/CAPSH_ADE05 CAPSH_ADE05] Major capsid protein that self-associates to form 240 hexon trimers, each in the shape of a hexagon, building most of the pseudo T=25 capsid. Assembled into trimeric units with the help of the chaperone shutoff protein (By similarity). Transported by pre-protein VI to the nucleus where it associates with other structural proteins to form an empty capsid. Might be involved, through its interaction with host dyneins, in the intracellular microtubule-dependent transport of incoming viral capsid to the nucleus. | |||
==See Also== | ==See Also== | ||
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[[Category: Human adenovirus 5]] | [[Category: Human adenovirus 5]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Baker | [[Category: Baker AH]] | ||
[[Category: Isaacs | [[Category: Isaacs NW]] | ||
[[Category: McVey | [[Category: McVey JH]] | ||
[[Category: Nicklin | [[Category: Nicklin SA]] | ||
[[Category: Roszak | [[Category: Roszak AW]] | ||
[[Category: Zhu | [[Category: Zhu Y]] | ||
Latest revision as of 16:27, 14 March 2024
Crystal structure of Adenovirus serotype 5 hexon at 1.6A resolutionCrystal structure of Adenovirus serotype 5 hexon at 1.6A resolution
Structural highlights
FunctionCAPSH_ADE05 Major capsid protein that self-associates to form 240 hexon trimers, each in the shape of a hexagon, building most of the pseudo T=25 capsid. Assembled into trimeric units with the help of the chaperone shutoff protein (By similarity). Transported by pre-protein VI to the nucleus where it associates with other structural proteins to form an empty capsid. Might be involved, through its interaction with host dyneins, in the intracellular microtubule-dependent transport of incoming viral capsid to the nucleus. See Also |
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