5sc0: Difference between revisions
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==CD44 PanDDA analysis group deposition -- The hyaluronan-binding domain of CD44 in complex with Z2856434899== | ==CD44 PanDDA analysis group deposition -- The hyaluronan-binding domain of CD44 in complex with Z2856434899== | ||
<StructureSection load='5sc0' size='340' side='right'caption='[[5sc0]]' scene=''> | <StructureSection load='5sc0' size='340' side='right'caption='[[5sc0]], [[Resolution|resolution]] 1.19Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5SC0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5SC0 FirstGlance]. <br> | <table><tr><td colspan='2'>[[5sc0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5SC0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5SC0 FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5sc0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5sc0 OCA], [https://pdbe.org/5sc0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5sc0 RCSB], [https://www.ebi.ac.uk/pdbsum/5sc0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5sc0 ProSAT]</span></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.192Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=T0Y:1-[(thiophen-3-yl)methyl]piperidin-4-ol'>T0Y</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5sc0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5sc0 OCA], [https://pdbe.org/5sc0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5sc0 RCSB], [https://www.ebi.ac.uk/pdbsum/5sc0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5sc0 ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/CD44_MOUSE CD44_MOUSE] Main cell surface receptor for hyaluronate. Adhesion to mucosal high endothelial venule and to types I and VI collagen. Probably involved in matrix adhesion, lymphocyte activation and lymph node homing. | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Mus musculus]] | |||
[[Category: Bezerra GA]] | [[Category: Bezerra GA]] | ||
[[Category: Bountra C]] | [[Category: Bountra C]] | ||