7lxd: Difference between revisions
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==== | ==Structure of yeast DNA Polymerase Zeta (apo)== | ||
<StructureSection load='7lxd' size='340' side='right'caption='[[7lxd]]' scene=''> | <StructureSection load='7lxd' size='340' side='right'caption='[[7lxd]], [[Resolution|resolution]] 4.11Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br> | <table><tr><td colspan='2'>[[7lxd]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7LXD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7LXD FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7lxd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7lxd OCA], [https://pdbe.org/7lxd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7lxd RCSB], [https://www.ebi.ac.uk/pdbsum/7lxd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7lxd ProSAT]</span></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.11Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7lxd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7lxd OCA], [https://pdbe.org/7lxd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7lxd RCSB], [https://www.ebi.ac.uk/pdbsum/7lxd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7lxd ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/DPOZ_YEAST DPOZ_YEAST] Nonessential DNA polymerase. Required for DNA damage induced mutagenesis. Involved in DNA repair, mitochondrial DNA repair and translesion synthesis. Translesion synthesis in S.cerevisiae may use a specialized DNA polymerase that is not required for other DNA replicative processes. Has a role in the bypass of abasic (AP) sites. Highly inefficient in incorporating nucleotides opposite the AP site, but efficiently extends from nucleotides, particularly an A, inserted opposite the lesion.<ref>PMID:11316789</ref> <ref>PMID:16452144</ref> <ref>PMID:2676986</ref> <ref>PMID:8658138</ref> | |||
==See Also== | |||
*[[DNA polymerase 3D structures|DNA polymerase 3D structures]] | |||
== References == | |||
<references/> | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: | [[Category: Saccharomyces cerevisiae S288C]] | ||
[[Category: Botuyan MV]] | |||
[[Category: Chan K-Y]] | |||
[[Category: Chiu P-L]] | |||
[[Category: Craig TA]] | |||
[[Category: Cui G]] | |||
[[Category: Kumar R]] | |||
[[Category: Mer G]] | |||
[[Category: Serkasevich RA]] | |||
[[Category: Truong CD]] | |||