7lum: Difference between revisions
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==== | ==Human TRiC in ATP/AlFx closed state== | ||
<StructureSection load='7lum' size='340' side='right'caption='[[7lum]]' scene=''> | <StructureSection load='7lum' size='340' side='right'caption='[[7lum]], [[Resolution|resolution]] 4.50Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br> | <table><tr><td colspan='2'>[[7lum]] is a 16 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7LUM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7LUM FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7lum FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7lum OCA], [https://pdbe.org/7lum PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7lum RCSB], [https://www.ebi.ac.uk/pdbsum/7lum PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7lum ProSAT]</span></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.5Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7lum FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7lum OCA], [https://pdbe.org/7lum PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7lum RCSB], [https://www.ebi.ac.uk/pdbsum/7lum PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7lum ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Disease == | |||
[https://www.uniprot.org/uniprot/TCPE_HUMAN TCPE_HUMAN] Hereditary sensory and autonomic neuropathy with spastic paraplegia. The disease is caused by mutations affecting the gene represented in this entry. | |||
== Function == | |||
[https://www.uniprot.org/uniprot/TCPE_HUMAN TCPE_HUMAN] Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Known to play a role, in vitro, in the folding of actin and tubulin.<ref>PMID:20080638</ref> | |||
==See Also== | |||
*[[Chaperonin 3D structures|Chaperonin 3D structures]] | |||
== References == | |||
<references/> | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: | [[Category: Aebersold R]] | ||
[[Category: Chiu W]] | |||
[[Category: Dermody TS]] | |||
[[Category: Frydman J]] | |||
[[Category: Gestaut D]] | |||
[[Category: Knowlton JJ]] | |||
[[Category: Leitner A]] | |||
[[Category: Ma B]] | |||
[[Category: Prasad BVV]] | |||
[[Category: Seven AB]] | |||
[[Category: Shanker S]] | |||
[[Category: Taylor G]] | |||
[[Category: Wilson GJ]] | |||
[[Category: Yates NA]] | |||
Latest revision as of 18:00, 6 March 2024
Human TRiC in ATP/AlFx closed stateHuman TRiC in ATP/AlFx closed state
Structural highlights
DiseaseTCPE_HUMAN Hereditary sensory and autonomic neuropathy with spastic paraplegia. The disease is caused by mutations affecting the gene represented in this entry. FunctionTCPE_HUMAN Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Known to play a role, in vitro, in the folding of actin and tubulin.[1] See AlsoReferences
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