3qc7: Difference between revisions

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<StructureSection load='3qc7' size='340' side='right'caption='[[3qc7]], [[Resolution|resolution]] 1.52&Aring;' scene=''>
<StructureSection load='3qc7' size='340' side='right'caption='[[3qc7]], [[Resolution|resolution]] 1.52&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3qc7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bpph2 Bpph2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QC7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QC7 FirstGlance]. <br>
<table><tr><td colspan='2'>[[3qc7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_virus_phi29 Bacillus virus phi29]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QC7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QC7 FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">8.5 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10756 BPPH2])</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.52&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qc7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qc7 OCA], [https://pdbe.org/3qc7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qc7 RCSB], [https://www.ebi.ac.uk/pdbsum/3qc7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qc7 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qc7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qc7 OCA], [https://pdbe.org/3qc7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qc7 RCSB], [https://www.ebi.ac.uk/pdbsum/3qc7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qc7 ProSAT]</span></td></tr>
</table>
</table>
<div style="background-color:#fffaf0;">
== Function ==
== Publication Abstract from PubMed ==
[https://www.uniprot.org/uniprot/CAPSF_BPPH2 CAPSF_BPPH2] Protein that forms the 55 capsid fibers. These fibers are not always present and may have been lost in some lab strains. They may enhance the attachment of the virions onto the host cell wall.<ref>PMID:409854</ref>  
The tailed bacteriophage 29 capsid is decorated with 55 fibers attached to quasi-3-fold symmetry positions. Each fiber is a homotrimer of gene product 8.5 (gp8.5) and consists of two major structural parts, a pseudohexagonal base and a protruding fibrous portion that is about 110 A in length. The crystal structure of the C-terminal fibrous portion (residues 112-280) has been determined to a resolution of 1.6 A. The structure is about 150 A long and shows three distinct structural domains designated as head, neck, and stem. The stem region is a unique three-stranded helix-turn-helix supercoil that has not previously been described. When fitted into a cryoelectron microscope reconstruction of the virus, the head structure corresponded to a disconnected density at the distal end of the fiber and the neck structure was located in weak density connecting it to the fiber. Thin section studies of Bacillus subtilis cells infected with fibered or fiberless 29 suggest that the fibers might enhance the attachment of the virions onto the host cell wall.
 
Structure of bacteriophage {phi}29 head fibers has a supercoiled triple repeating helix-turn-helix motif.,Xiang Y, Rossmann MG Proc Natl Acad Sci U S A. 2011 Mar 7. PMID:21383126<ref>PMID:21383126</ref>
 
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
<div class="pdbe-citations 3qc7" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bpph2]]
[[Category: Bacillus virus phi29]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Rossmann, M G]]
[[Category: Rossmann MG]]
[[Category: Xiang, Y]]
[[Category: Xiang Y]]
[[Category: Supercoiled triple repeating helix-turn-helix]]
[[Category: Viral protein]]

Latest revision as of 13:46, 21 February 2024

The structure of bacteriophage phi29 head fibers has a supercoiled triple repeating helix-turn-helix motifThe structure of bacteriophage phi29 head fibers has a supercoiled triple repeating helix-turn-helix motif

Structural highlights

3qc7 is a 1 chain structure with sequence from Bacillus virus phi29. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.52Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

CAPSF_BPPH2 Protein that forms the 55 capsid fibers. These fibers are not always present and may have been lost in some lab strains. They may enhance the attachment of the virions onto the host cell wall.[1]

References

  1. ↑ Reilly BE, Nelson RA, Anderson DL. Morphogenesis of bacteriophage phi 29 of Bacillus subtilis: mapping and functional analysis of the head fiber gene. J Virol. 1977 Oct;24(1):363-77. PMID:409854

3qc7, resolution 1.52Å

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