3dal: Difference between revisions
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<StructureSection load='3dal' size='340' side='right'caption='[[3dal]], [[Resolution|resolution]] 1.65Å' scene=''> | <StructureSection load='3dal' size='340' side='right'caption='[[3dal]], [[Resolution|resolution]] 1.65Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3dal]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[3dal]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DAL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3DAL FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3dal FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dal OCA], [https://pdbe.org/3dal PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3dal RCSB], [https://www.ebi.ac.uk/pdbsum/3dal PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3dal ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3dal FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dal OCA], [https://pdbe.org/3dal PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3dal RCSB], [https://www.ebi.ac.uk/pdbsum/3dal PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3dal ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/PRDM1_HUMAN PRDM1_HUMAN] Transcriptional repressor that binds specifically to the PRDI element in the promoter of the beta-interferon gene. Drives the maturation of B-lymphocytes into Ig secreting cells. | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Amaya | [[Category: Amaya MF]] | ||
[[Category: Antoshenko | [[Category: Antoshenko T]] | ||
[[Category: Arrowsmith | [[Category: Arrowsmith CH]] | ||
[[Category: Bochkarev | [[Category: Bochkarev A]] | ||
[[Category: Bountra | [[Category: Bountra C]] | ||
[[Category: Dong | [[Category: Dong A]] | ||
[[Category: Edwards | [[Category: Edwards AM]] | ||
[[Category: Loppnau | [[Category: Loppnau P]] | ||
[[Category: Min | [[Category: Min J]] | ||
[[Category: Plotnikov | [[Category: Plotnikov AN]] | ||
[[Category: Weigelt J]] | |||
[[Category: Weigelt | [[Category: Wu H]] | ||
[[Category: Wu | [[Category: Zeng H]] | ||
[[Category: Zeng | |||
Latest revision as of 12:40, 21 February 2024
Methyltransferase domain of human PR domain-containing protein 1Methyltransferase domain of human PR domain-containing protein 1
Structural highlights
FunctionPRDM1_HUMAN Transcriptional repressor that binds specifically to the PRDI element in the promoter of the beta-interferon gene. Drives the maturation of B-lymphocytes into Ig secreting cells. Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. |
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