2ow4: Difference between revisions

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 <StructureSection load='2ow4' size='340' side='right'caption='[[2ow4]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[2ow4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Canavalia_maritima Canavalia maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OW4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OW4 FirstGlance]. <br>
+<table><tr><td colspan='2'>[[2ow4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Canavalia_rosea Canavalia rosea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OW4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OW4 FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=MMA:O1-METHYL-MANNOSE'>MMA</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
-<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2ovu|2ovu]], [[2p2k|2p2k]]</div></td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=MMA:O1-METHYL-MANNOSE'>MMA</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
 <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ow4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ow4 OCA], [https://pdbe.org/2ow4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ow4 RCSB], [https://www.ebi.ac.uk/pdbsum/2ow4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ow4 ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[https://www.uniprot.org/uniprot/CONA_CANRO CONA_CANRO]] Glucose/D-mannose specific lectin.
+[https://www.uniprot.org/uniprot/CONA_CANRO CONA_CANRO] Glucose/D-mannose specific lectin.
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]
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 </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ow4 ConSurf].
 <div style="clear:both"></div>
-<div style="background-color:#fffaf0;">
-== Publication Abstract from PubMed ==
-Plant lectins, especially those purified from species of the Leguminosae family, represent the best studied group of carbohydrate-binding proteins. The legume lectins from Diocleinae subtribe are highly similar proteins that present significant differences in the potency/efficacy of their biological activities. The structural studies of the interactions between lectins and sugars may clarify the origin of the distinct biological activities observed in this high similar class of proteins. In this way, this work presents a crystallographic study of the ConM and CGL (agglutinins from Canavalia maritima and Canavalia gladiata, respectively) in the following complexes: ConM/CGL:Man(alpha1-2)Man(alpha1-O)Me, ConM/CGL:Man(alpha1-3)Man(alpha1-O)Me and ConM/CGL:Man(alpha1-4)Man(alpha1-O)Me, which crystallized in different conditions and space group from the native proteins. The structures were solved by molecular replacement, presenting satisfactory values for R(factor) and R(free). Comparisons between ConM, CGL and ConA (Canavalia ensiformis lectin) binding mode with the dimannosides in subject, presented different interactions patterns, which may account for a structural explanation of the distincts biological properties observed in the lectins of Diocleinae subtribe.
-Structural analysis of Canavalia maritima and Canavalia gladiata lectins complexed with different dimannosides: new insights into the understanding of the structure-biological activity relationship in legume lectins.,Bezerra GA, Oliveira TM, Moreno FB, de Souza EP, da Rocha BA, Benevides RG, Delatorre P, de Azevedo WF Jr, Cavada BS J Struct Biol. 2007 Nov;160(2):168-76. Epub 2007 Aug 16. PMID:17881248<ref>PMID:17881248</ref>
-From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
-</div>
-<div class="pdbe-citations 2ow4" style="background-color:#fffaf0;"></div>
 ==See Also==
 *[[Concanavalin 3D structures|Concanavalin 3D structures]]
-== References ==
-<references/>
 __TOC__
 </StructureSection>
-[[Category: Canavalia maritima]]
+[[Category: Canavalia rosea]]
 [[Category: Large Structures]]
-[[Category: Azevedo, W F.de]]
+[[Category: Benevides RG]]
-[[Category: Benevides, R G]]
+[[Category: Bezerra GA]]
-[[Category: Bezerra, G A]]
+[[Category: Cavada BS]]
-[[Category: Cavada, B S]]
+[[Category: Delatorre P]]
-[[Category: Delatorre, P]]
+[[Category: Moreno FBMB]]
-[[Category: Moreno, F B.M B]]
+[[Category: Da Rocha BAM]]
-[[Category: Oliveira, T M.de]]
+[[Category: De Azevedo Jr WF]]
-[[Category: Rocha, B A.M da]]
+[[Category: De Oliveira TM]]
-[[Category: Souza, E M.de]]
+[[Category: De Souza EM]]
-[[Category: Lectin]]
-[[Category: Man1-2man-ome]]
-[[Category: Sugar binding protein]]