2f0t: Difference between revisions

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<StructureSection load='2f0t' size='340' side='right'caption='[[2f0t]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
<StructureSection load='2f0t' size='340' side='right'caption='[[2f0t]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2f0t]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"micrococcus_aureus"_(rosenbach_1884)_zopf_1885 "micrococcus aureus" (rosenbach 1884) zopf 1885]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F0T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2F0T FirstGlance]. <br>
<table><tr><td colspan='2'>[[2f0t]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F0T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2F0T FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1ey0|1ey0]], [[2exz|2exz]], [[2ey1|2ey1]], [[2ey2|2ey2]], [[2ey5|2ey5]], [[2ey6|2ey6]], [[2eyf|2eyf]], [[2eyh|2eyh]], [[2eyj|2eyj]], [[2eyl|2eyl]], [[2eym|2eym]], [[2eyo|2eyo]], [[2eyp|2eyp]], [[2f0d|2f0d]], [[2f0e|2f0e]], [[2f0f|2f0f]], [[2f0g|2f0g]], [[2f0h|2f0h]], [[2f0i|2f0i]], [[2f0j|2f0j]], [[2f0k|2f0k]], [[2f0l|2f0l]], [[2f0m|2f0m]], [[2f0n|2f0n]], [[2f0o|2f0o]], [[2f0p|2f0p]], [[2f0q|2f0q]], [[2f0s|2f0s]], [[2f0u|2f0u]], [[2f0v|2f0v]], [[2f0w|2f0w]]</div></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">nuc ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1280 "Micrococcus aureus" (Rosenbach 1884) Zopf 1885])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Micrococcal_nuclease Micrococcal nuclease], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.31.1 3.1.31.1] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2f0t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f0t OCA], [https://pdbe.org/2f0t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2f0t RCSB], [https://www.ebi.ac.uk/pdbsum/2f0t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2f0t ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2f0t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f0t OCA], [https://pdbe.org/2f0t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2f0t RCSB], [https://www.ebi.ac.uk/pdbsum/2f0t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2f0t ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/NUC_STAAU NUC_STAAU]] Enzyme that catalyzes the hydrolysis of both DNA and RNA at the 5' position of the phosphodiester bond.  
[https://www.uniprot.org/uniprot/NUC_STAAU NUC_STAAU] Enzyme that catalyzes the hydrolysis of both DNA and RNA at the 5' position of the phosphodiester bond.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Micrococcal nuclease]]
[[Category: Staphylococcus aureus]]
[[Category: Lu, J Z]]
[[Category: Lu JZ]]
[[Category: Sakon, J]]
[[Category: Sakon J]]
[[Category: Stites, W E]]
[[Category: Stites WE]]
[[Category: Calcium]]
[[Category: Dna hydrolase]]
[[Category: Endonuclease]]
[[Category: Hydrolase]]
[[Category: Rna hydrolase]]
[[Category: Signal]]

Latest revision as of 12:20, 14 February 2024

Crystal structure of Staphylococcal nuclease mutant V66L/V99ICrystal structure of Staphylococcal nuclease mutant V66L/V99I

Structural highlights

2f0t is a 1 chain structure with sequence from Staphylococcus aureus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.7Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

NUC_STAAU Enzyme that catalyzes the hydrolysis of both DNA and RNA at the 5' position of the phosphodiester bond.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

2f0t, resolution 1.70Å

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