2y1z: Difference between revisions
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<StructureSection load='2y1z' size='340' side='right'caption='[[2y1z]], [[Resolution|resolution]] 2.50Å' scene=''> | <StructureSection load='2y1z' size='340' side='right'caption='[[2y1z]], [[Resolution|resolution]] 2.50Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2y1z]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[2y1z]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y1Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Y1Z FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=MRD:(4R)-2-METHYLPENTANE-2,4-DIOL'>MRD</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2y1z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y1z OCA], [https://pdbe.org/2y1z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2y1z RCSB], [https://www.ebi.ac.uk/pdbsum/2y1z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2y1z ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2y1z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y1z OCA], [https://pdbe.org/2y1z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2y1z RCSB], [https://www.ebi.ac.uk/pdbsum/2y1z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2y1z ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Disease == | == Disease == | ||
[https://www.uniprot.org/uniprot/CRYAB_HUMAN CRYAB_HUMAN] Posterior polar cataract;Alpha-crystallinopathy;Zonular cataract;Familial isolated dilated cardiomyopathy;Fatal infantile hypertonic myofibrillar myopathy. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. | |||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/CRYAB_HUMAN CRYAB_HUMAN] May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Bagneris | [[Category: Bagneris C]] | ||
[[Category: Clark | [[Category: Clark AR]] | ||
[[Category: Keep | [[Category: Keep NH]] | ||
[[Category: Naylor | [[Category: Naylor CE]] | ||
[[Category: Slingsby | [[Category: Slingsby C]] | ||