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==Crystal Structure of Bacillus subtilis Penicillin Binding Protein 3== | ==Crystal Structure of Bacillus subtilis Penicillin Binding Protein 3== | ||
<StructureSection load='7bn9' size='340' side='right'caption='[[7bn9]]' scene=''> | <StructureSection load='7bn9' size='340' side='right'caption='[[7bn9]], [[Resolution|resolution]] 2.65Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7BN9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7BN9 FirstGlance]. <br> | <table><tr><td colspan='2'>[[7bn9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis_subsp._subtilis_str._168 Bacillus subtilis subsp. subtilis str. 168]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7BN9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7BN9 FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7bn9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7bn9 OCA], [https://pdbe.org/7bn9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7bn9 RCSB], [https://www.ebi.ac.uk/pdbsum/7bn9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7bn9 ProSAT]</span></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.65Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7bn9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7bn9 OCA], [https://pdbe.org/7bn9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7bn9 RCSB], [https://www.ebi.ac.uk/pdbsum/7bn9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7bn9 ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/PBPC_BACSU PBPC_BACSU] Penicillin-binding proteins (PBPs) function in the late steps of murein biosynthesis (Probable). Probably required for both cortical and vegetative peptidoglycan synthesis (Probable). Although not usually required for cell division, in the absence of PBP 2B (pbpB) it becomes essential. Confers resistance to oxacillin and cephalexin (PubMed:28792086).<ref>PMID:28792086</ref> <ref>PMID:3080407</ref> | |||
==See Also== | |||
*[[Penicillin-binding protein 3D structures|Penicillin-binding protein 3D structures]] | |||
== References == | |||
<references/> | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Bacillus subtilis subsp. subtilis str. 168]] | |||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Lewis RJ]] | [[Category: Lewis RJ]] | ||
[[Category: Rao VA]] | [[Category: Rao VA]] | ||
Latest revision as of 15:31, 1 February 2024
Crystal Structure of Bacillus subtilis Penicillin Binding Protein 3Crystal Structure of Bacillus subtilis Penicillin Binding Protein 3
Structural highlights
FunctionPBPC_BACSU Penicillin-binding proteins (PBPs) function in the late steps of murein biosynthesis (Probable). Probably required for both cortical and vegetative peptidoglycan synthesis (Probable). Although not usually required for cell division, in the absence of PBP 2B (pbpB) it becomes essential. Confers resistance to oxacillin and cephalexin (PubMed:28792086).[1] [2] See AlsoReferences
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