7a28: Difference between revisions
Jump to navigation
Jump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
==Crystal structure of T. brucei PDE-B1 catalytic domain with inhibitor NPD-617== | ==Crystal structure of T. brucei PDE-B1 catalytic domain with inhibitor NPD-617== | ||
<StructureSection load='7a28' size='340' side='right'caption='[[7a28]]' scene=''> | <StructureSection load='7a28' size='340' side='right'caption='[[7a28]], [[Resolution|resolution]] 1.89Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7A28 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7A28 FirstGlance]. <br> | <table><tr><td colspan='2'>[[7a28]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_brucei Trypanosoma brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7A28 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7A28 FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7a28 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7a28 OCA], [https://pdbe.org/7a28 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7a28 RCSB], [https://www.ebi.ac.uk/pdbsum/7a28 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7a28 ProSAT]</span></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.89Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GAI:GUANIDINE'>GAI</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=QWT:1-cycloheptyl-3-(4-methoxy-3-{4-[4-(1H-1,2,3,4-tetrazol-5-yl)phenoxy]butoxy}phenyl)-4,4-dimethyl-4,5-dihydro-1H-pyrazol-5-one'>QWT</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7a28 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7a28 OCA], [https://pdbe.org/7a28 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7a28 RCSB], [https://www.ebi.ac.uk/pdbsum/7a28 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7a28 ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/Q8WQX9_9TRYP Q8WQX9_9TRYP] | |||
==See Also== | |||
*[[Phosphodiesterase 3D structures|Phosphodiesterase 3D structures]] | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Trypanosoma brucei]] | |||
[[Category: Blaazer AR]] | [[Category: Blaazer AR]] | ||
[[Category: Brown DG]] | [[Category: Brown DG]] | ||
Latest revision as of 15:02, 1 February 2024
Crystal structure of T. brucei PDE-B1 catalytic domain with inhibitor NPD-617Crystal structure of T. brucei PDE-B1 catalytic domain with inhibitor NPD-617
Structural highlights
FunctionSee Also |
| ||||||||||||||||||