7a04: Difference between revisions
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<StructureSection load='7a04' size='340' side='right'caption='[[7a04]], [[Resolution|resolution]] 2.15Å' scene=''> | <StructureSection load='7a04' size='340' side='right'caption='[[7a04]], [[Resolution|resolution]] 2.15Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[7a04]] is a 2 chain structure with sequence from [ | <table><tr><td colspan='2'>[[7a04]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7A04 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7A04 FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=QTK:1-(phenylmethyl)-4-pyrrolidin-1-yl-pyridin-1-ium'>QTK</scene> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=QTK:1-(phenylmethyl)-4-pyrrolidin-1-yl-pyridin-1-ium'>QTK</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7a04 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7a04 OCA], [https://pdbe.org/7a04 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7a04 RCSB], [https://www.ebi.ac.uk/pdbsum/7a04 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7a04 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/CHKA_HUMAN CHKA_HUMAN] Has a key role in phospholipid biosynthesis and may contribute to tumor cell growth. Catalyzes the first step in phosphatidylcholine biosynthesis. Contributes to phosphatidylethanolamine biosynthesis. Phosphorylates choline and ethanolamine. Has higher activity with choline.<ref>PMID:19915674</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</div> | </div> | ||
<div class="pdbe-citations 7a04" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 7a04" style="background-color:#fffaf0;"></div> | ||
==See Also== | |||
*[[Choline kinase 3D structures|Choline kinase 3D structures]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Ballarotto | [[Category: Ballarotto M]] | ||
[[Category: Carrasco-Jimenez | [[Category: Carrasco-Jimenez MP]] | ||
[[Category: Hurtado-Guerrero | [[Category: Castro Navas FC]] | ||
[[Category: Lopez-Cara | [[Category: Hurtado-Guerrero R]] | ||
[[Category: Macchiarulo | [[Category: Lopez-Cara LC]] | ||
[[Category: Marco | [[Category: Macchiarulo A]] | ||
[[Category: Mariotto | [[Category: Marco C]] | ||
[[Category: Mariotto E]] | |||
[[Category: Rubbini | [[Category: Rubbini G]] | ||
[[Category: Serran-Aguilera | [[Category: Serran-Aguilera L]] | ||
[[Category: Viola | [[Category: Viola G]] | ||