6ym8: Difference between revisions

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==Crystal structure of YTHDC1 with compound YLI_DC1_002==
==Crystal structure of YTHDC1 with compound YLI_DC1_002==
<StructureSection load='6ym8' size='340' side='right'caption='[[6ym8]]' scene=''>
<StructureSection load='6ym8' size='340' side='right'caption='[[6ym8]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6YM8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6YM8 FirstGlance]. <br>
<table><tr><td colspan='2'>[[6ym8]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6YM8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6YM8 FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ym8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ym8 OCA], [https://pdbe.org/6ym8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ym8 RCSB], [https://www.ebi.ac.uk/pdbsum/6ym8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ym8 ProSAT]</span></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=OYN:2-chloranyl-~{N}-methyl-9~{H}-purin-6-amine'>OYN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ym8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ym8 OCA], [https://pdbe.org/6ym8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ym8 RCSB], [https://www.ebi.ac.uk/pdbsum/6ym8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ym8 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/YTDC1_HUMAN YTDC1_HUMAN] RNA-binding protein that regulates alternative splice site selection.<ref>PMID:20167602</ref>
== References ==
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Bedi RK]]
[[Category: Bedi RK]]

Latest revision as of 16:30, 24 January 2024

Crystal structure of YTHDC1 with compound YLI_DC1_002Crystal structure of YTHDC1 with compound YLI_DC1_002

Structural highlights

6ym8 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.5Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

YTDC1_HUMAN RNA-binding protein that regulates alternative splice site selection.[1]

References

  1. ↑ Zhang Z, Theler D, Kaminska KH, Hiller M, de la Grange P, Pudimat R, Rafalska I, Heinrich B, Bujnicki JM, Allain FH, Stamm S. The YTH domain is a novel RNA binding domain. J Biol Chem. 2010 May 7;285(19):14701-10. doi: 10.1074/jbc.M110.104711. Epub 2010, Feb 18. PMID:20167602 doi:http://dx.doi.org/10.1074/jbc.M110.104711

6ym8, resolution 1.50Å

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