6sdx: Difference between revisions

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<StructureSection load='6sdx' size='340' side='right'caption='[[6sdx]], [[Resolution|resolution]] 2.65&Aring;' scene=''>
<StructureSection load='6sdx' size='340' side='right'caption='[[6sdx]], [[Resolution|resolution]] 2.65&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6sdx]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6SDX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6SDX FirstGlance]. <br>
<table><tr><td colspan='2'>[[6sdx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium Salmonella enterica subsp. enterica serovar Typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6SDX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6SDX FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AGS:PHOSPHOTHIOPHOSPHORIC+ACID-ADENYLATE+ESTER'>AGS</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.645&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6sdx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6sdx OCA], [http://pdbe.org/6sdx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6sdx RCSB], [http://www.ebi.ac.uk/pdbsum/6sdx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6sdx ProSAT]</span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AGS:PHOSPHOTHIOPHOSPHORIC+ACID-ADENYLATE+ESTER'>AGS</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6sdx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6sdx OCA], [https://pdbe.org/6sdx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6sdx RCSB], [https://www.ebi.ac.uk/pdbsum/6sdx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6sdx ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SCTN1_SALTY SCTN1_SALTY] ATPase component of the type III secretion system (T3SS), also called injectisome, which is used to inject bacterial effector proteins into eukaryotic host cells (PubMed:15060043, PubMed:16208377, PubMed:26170413). Acts as a molecular motor to provide the energy that is required for the export of proteins (Probable). Required for type III secretion apparatus (T3SA) formation, proper protein secretion, host cell invasion and virulence (PubMed:8045880, PubMed:14762212, PubMed:15060043, PubMed:26170413). May play a critical role in T3SS substrate recognition, disassembly of the effector/chaperone complex and unfolding of the effector in an ATP-dependent manner prior to secretion (PubMed:16208377). Releases the effector protein SptP from the chaperone SicP in an ATP-dependent manner (PubMed:16208377).<ref>PMID:14762212</ref> <ref>PMID:15060043</ref> <ref>PMID:16208377</ref> <ref>PMID:26170413</ref> <ref>PMID:8045880</ref> <ref>PMID:8045880</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 6sdx" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 6sdx" style="background-color:#fffaf0;"></div>
==See Also==
*[[ATPase 3D structures|ATPase 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Bernal, I]]
[[Category: Salmonella enterica subsp. enterica serovar Typhimurium]]
[[Category: Flacht, L]]
[[Category: Bernal I]]
[[Category: Kolbe, M]]
[[Category: Flacht L]]
[[Category: Lunelli, M]]
[[Category: Kolbe M]]
[[Category: Roemermann, J]]
[[Category: Lunelli M]]
[[Category: Uetrecht, C]]
[[Category: Roemermann J]]
[[Category: Atpase]]
[[Category: Uetrecht C]]
[[Category: Bacterial pathogenesis]]
[[Category: Crystallography]]
[[Category: Hydrolase]]
[[Category: Salmonella enterica]]

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