6rz4: Difference between revisions

← Older edit

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 3: / Line 3: @@
 <StructureSection load='6rz4' size='340' side='right'caption='[[6rz4]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[6rz4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6RZ4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6RZ4 FirstGlance]. <br>
+<table><tr><td colspan='2'>[[6rz4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6RZ4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6RZ4 FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=KNT:pranlukast'>KNT</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=OLA:OLEIC+ACID'>OLA</scene>, <scene name='pdbligand=OLC:(2R)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLC</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
-<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CYSLTR1, CYSLT1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=KNT:pranlukast'>KNT</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=OLA:OLEIC+ACID'>OLA</scene>, <scene name='pdbligand=OLC:(2R)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLC</scene></td></tr>
 <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6rz4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6rz4 OCA], [https://pdbe.org/6rz4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6rz4 RCSB], [https://www.ebi.ac.uk/pdbsum/6rz4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6rz4 ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[https://www.uniprot.org/uniprot/CLTR1_HUMAN CLTR1_HUMAN]] Receptor for cysteinyl leukotrienes mediating bronchoconstriction of individuals with and without asthma. Stimulation by LTD4 results in the contraction and proliferation of smooth muscle, edema, eosinophil migration and damage to the mucus layer in the lung. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTD4 >> LTE4 = LTC4 >> LTB4.
+[https://www.uniprot.org/uniprot/C562_ECOLX C562_ECOLX] Electron-transport protein of unknown function.[https://www.uniprot.org/uniprot/CLTR1_HUMAN CLTR1_HUMAN] Receptor for cysteinyl leukotrienes mediating bronchoconstriction of individuals with and without asthma. Stimulation by LTD4 results in the contraction and proliferation of smooth muscle, edema, eosinophil migration and damage to the mucus layer in the lung. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTD4 >> LTE4 = LTC4 >> LTB4.
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
@@ Line 23: / Line 23: @@
 __TOC__
 </StructureSection>
-[[Category: Bacillus coli migula 1895]]
+[[Category: Escherichia coli]]
+[[Category: Homo sapiens]]
 [[Category: Large Structures]]
-[[Category: Batyuk, A]]
+[[Category: Batyuk A]]
-[[Category: Besserer-Offroy, E]]
+[[Category: Besserer-Offroy E]]
-[[Category: Bogorodskiy, A]]
+[[Category: Bogorodskiy A]]
-[[Category: Borshchevskiy, V]]
+[[Category: Borshchevskiy V]]
-[[Category: Brouillette, R]]
+[[Category: Brouillette R]]
-[[Category: Cherezov, V]]
+[[Category: Cherezov V]]
-[[Category: Edelweiss, E]]
+[[Category: Edelweiss E]]
-[[Category: Gordeliy, V]]
+[[Category: Gordeliy V]]
-[[Category: Gusach, A]]
+[[Category: Gusach A]]
-[[Category: Han, G W]]
+[[Category: Han GW]]
-[[Category: Ishchenko, A]]
+[[Category: Ishchenko A]]
-[[Category: Katritch, V]]
+[[Category: Katritch V]]
-[[Category: Liu, W]]
+[[Category: Liu W]]
-[[Category: Longpre, J M]]
+[[Category: Longpre JM]]
-[[Category: Luginina, A]]
+[[Category: Luginina A]]
-[[Category: Lyapina, E]]
+[[Category: Lyapina E]]
-[[Category: Marin, E]]
+[[Category: Marin E]]
-[[Category: Mishin, A]]
+[[Category: Mishin A]]
-[[Category: Patel, N]]
+[[Category: Patel N]]
-[[Category: Polovinkin, V]]
+[[Category: Polovinkin V]]
-[[Category: Popov, P]]
+[[Category: Popov P]]
-[[Category: Safronova, N]]
+[[Category: Safronova N]]
-[[Category: Sarret, P]]
+[[Category: Sarret P]]
-[[Category: Shiryaeva, A]]
+[[Category: Shiryaeva A]]
-[[Category: Bril]]
-[[Category: Cyslt1]]
-[[Category: Cyslt1r asthma]]
-[[Category: Cysltr1]]
-[[Category: Cysteinyl leukotriene]]
-[[Category: Cysteinyl leukotriene receptor 1]]
-[[Category: Gpcr]]
-[[Category: Lcp]]
-[[Category: Ltd4]]
-[[Category: Membrane protein]]
-[[Category: Pranlukast]]
-[[Category: Sodium site]]