Carvedilol: Difference between revisions
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<StructureSection load='' size='340' side='right' caption=' | <StructureSection load='' size='340' side='right' caption='Carvedilol' scene='10/1009520/Cv/2'> | ||
Carvedilol, sold under the brand name Coreg among others, is a medication used to treat high blood pressure, congestive heart failure (CHF), and left ventricular dysfunction in people who are otherwise stable. For high blood pressure, it is generally a second-line treatment.<ref name="a1">[https://www.drugs.com/monograph/carvedilol.html "Carvedilol Monograph for Professionals".] Drugs.com. AHFS. Retrieved 24 December 2018.</ref> See also [https://en.wikipedia.org/wiki/Carvedilol Carvedilol]. | Carvedilol, sold under the brand name Coreg among others, is a medication used to treat high blood pressure, congestive heart failure (CHF), and left ventricular dysfunction in people who are otherwise stable. For high blood pressure, it is generally a second-line treatment.<ref name="a1">[https://www.drugs.com/monograph/carvedilol.html "Carvedilol Monograph for Professionals".] Drugs.com. AHFS. Retrieved 24 December 2018.</ref> See also [https://en.wikipedia.org/wiki/Carvedilol Carvedilol]. | ||
Latest revision as of 10:38, 22 January 2024
Carvedilol, sold under the brand name Coreg among others, is a medication used to treat high blood pressure, congestive heart failure (CHF), and left ventricular dysfunction in people who are otherwise stable. For high blood pressure, it is generally a second-line treatment.[1] See also Carvedilol. Carvedilol is both a non-selective β-adrenergic receptor antagonist (β1, β2) and an α-adrenergic receptor antagonist (α1). See also Adrenergic receptor. The S(–) enantiomer accounts for the beta-blocking activity whereas the S(–) and R(+) enantiomers have alpha-blocking activity.[2] The affinity (Ki) of carvedilol for the β-adrenergic receptors is 0.32 nM for the human β1-adrenergic receptor and 0.13 to 0.40 nM for the β2-adrenergic receptor.[3] (4amj). . |
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ReferencesReferences
- ↑ "Carvedilol Monograph for Professionals". Drugs.com. AHFS. Retrieved 24 December 2018.
- ↑ "Coreg - Food and Drug Administration" (PDF).
- ↑ "Carvedilol | Ligand page | IUPHAR/BPS Guide to PHARMACOLOGY"