3f70: Difference between revisions

<table><tr><td colspan='2'>[[3f70]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3dbb 3dbb]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3F70 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3F70 FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>

<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MLZ:N-METHYL-LYSINE'>MLZ</scene></td></tr>

[https://www.uniprot.org/uniprot/LMBL2_HUMAN LMBL2_HUMAN] Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Its association with a chromatin-remodeling complex suggests that it may contribute to prevent expression of genes that trigger the cell into mitosis. Binds to monomethylated and dimethylated 'Lys-20' on histone H4. Binds histone H3 peptides that are monomethylated or dimethylated on 'Lys-4', 'Lys-9' or 'Lys-27'.<ref>PMID:19233876</ref>  

[[Category: Homo sapiens]]

[[Category: Allali-Hassani A]]

[[Category: Arrowsmith CH]]

[[Category: Botchkarev A]]

[[Category: Bountra C]]

[[Category: Crombet L]]

[[Category: Dong A]]

[[Category: Edwards AM]]

[[Category: Guo Y]]

[[Category: Kozieradzki I]]

[[Category: Loppnau P]]

[[Category: Mackenzie F]]

[[Category: Min J]]

[[Category: Pan P]]

[[Category: Qi C]]

[[Category: Read R]]

[[Category: Vedadi M]]

[[Category: Weigelt J]]

[[Category: Zhu H]]