2jhb: Difference between revisions
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==CORE BINDING FACTOR BETA== | ==CORE BINDING FACTOR BETA== | ||
<StructureSection load='2jhb' size='340' side='right'caption='[[2jhb | <StructureSection load='2jhb' size='340' side='right'caption='[[2jhb]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2jhb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[2jhb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JHB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JHB FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jhb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jhb OCA], [https://pdbe.org/2jhb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jhb RCSB], [https://www.ebi.ac.uk/pdbsum/2jhb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jhb ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jhb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jhb OCA], [https://pdbe.org/2jhb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jhb RCSB], [https://www.ebi.ac.uk/pdbsum/2jhb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jhb ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/PEBB_MOUSE PEBB_MOUSE] CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, LCK, IL3 and GM-CSF promoters. CBFB enhances DNA binding by RUNX1. | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: | [[Category: Mus musculus]] | ||
[[Category: Bushweller | [[Category: Bushweller JH]] | ||
[[Category: Huang | [[Category: Huang X]] | ||
[[Category: Peng | [[Category: Peng J]] | ||
[[Category: Speck | [[Category: Speck NA]] | ||