1v95: Difference between revisions

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==Solution Structure of Anticodon Binding Domain from Nuclear Receptor Coactivator 5 (Human KIAA1637 Protein)==
==Solution Structure of Anticodon Binding Domain from Nuclear Receptor Coactivator 5 (Human KIAA1637 Protein)==
<StructureSection load='1v95' size='340' side='right'caption='[[1v95]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='1v95' size='340' side='right'caption='[[1v95]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1v95]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V95 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1V95 FirstGlance]. <br>
<table><tr><td colspan='2'>[[1v95]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V95 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1V95 FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">KAZUSA cDNA fj00747s1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1v95 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v95 OCA], [https://pdbe.org/1v95 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1v95 RCSB], [https://www.ebi.ac.uk/pdbsum/1v95 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1v95 ProSAT], [https://www.topsan.org/Proteins/RSGI/1v95 TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1v95 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v95 OCA], [https://pdbe.org/1v95 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1v95 RCSB], [https://www.ebi.ac.uk/pdbsum/1v95 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1v95 ProSAT], [https://www.topsan.org/Proteins/RSGI/1v95 TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/NCOA5_HUMAN NCOA5_HUMAN]] Nuclear receptor coregulator that can have both coactivator and corepressor functions. Interacts with nuclear receptors for steroids (ESR1 and ESR2) independently of the steroid binding domain (AF-2) of the ESR receptors, and with the orphan nuclear receptor NR1D2. Involved in the coactivation of nuclear steroid receptors (ER) as well as the corepression of MYC in response to 17-beta-estradiol (E2).<ref>PMID:15073177</ref>
[https://www.uniprot.org/uniprot/NCOA5_HUMAN NCOA5_HUMAN] Nuclear receptor coregulator that can have both coactivator and corepressor functions. Interacts with nuclear receptors for steroids (ESR1 and ESR2) independently of the steroid binding domain (AF-2) of the ESR receptors, and with the orphan nuclear receptor NR1D2. Involved in the coactivation of nuclear steroid receptors (ER) as well as the corepression of MYC in response to 17-beta-estradiol (E2).<ref>PMID:15073177</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Inoue, M]]
[[Category: Inoue M]]
[[Category: Kigawa, T]]
[[Category: Kigawa T]]
[[Category: Koshiba, S]]
[[Category: Koshiba S]]
[[Category: Structural genomic]]
[[Category: Tochio N]]
[[Category: Tochio, N]]
[[Category: Yokoyama S]]
[[Category: Yokoyama, S]]
[[Category: Zhao C]]
[[Category: Zhao, C]]
[[Category: Nuclear receptor coactivator 5]]
[[Category: Rna binding protein]]
[[Category: Rsgi]]

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