1udl: Difference between revisions
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==The solution structure of the fifth SH3 domain of intersectin 2 (KIAA1256)== | ==The solution structure of the fifth SH3 domain of intersectin 2 (KIAA1256)== | ||
<StructureSection load='1udl' size='340' side='right'caption='[[1udl | <StructureSection load='1udl' size='340' side='right'caption='[[1udl]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1udl]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[1udl]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UDL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1UDL FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1udl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1udl OCA], [https://pdbe.org/1udl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1udl RCSB], [https://www.ebi.ac.uk/pdbsum/1udl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1udl ProSAT], [https://www.topsan.org/Proteins/RSGI/1udl TOPSAN]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1udl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1udl OCA], [https://pdbe.org/1udl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1udl RCSB], [https://www.ebi.ac.uk/pdbsum/1udl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1udl ProSAT], [https://www.topsan.org/Proteins/RSGI/1udl TOPSAN]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/ITSN2_HUMAN ITSN2_HUMAN] Adapter protein that may provide indirect link between the endocytic membrane traffic and the actin assembly machinery. May regulate the formation of clathrin-coated vesicles (CCPs). Seems to be involved in CCPs maturation including invagination or budding. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR).<ref>PMID:19458185</ref> <ref>PMID:22648170</ref> | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Goroncy | [[Category: Goroncy A]] | ||
[[Category: Inoue | [[Category: Inoue M]] | ||
[[Category: Kigawa | [[Category: Kigawa T]] | ||
[[Category: Kobayashi | [[Category: Kobayashi N]] | ||
[[Category: Koshiba | [[Category: Koshiba S]] | ||
[[Category: Tochio N]] | |||
[[Category: Tochio | [[Category: Yokoyama S]] | ||
[[Category: Yokoyama | |||