1qfp: Difference between revisions

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<StructureSection load='1qfp' size='340' side='right'caption='[[1qfp]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
<StructureSection load='1qfp' size='340' side='right'caption='[[1qfp]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1qfp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QFP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1QFP FirstGlance]. <br>
<table><tr><td colspan='2'>[[1qfp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QFP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1QFP FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1qfp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qfp OCA], [https://pdbe.org/1qfp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1qfp RCSB], [https://www.ebi.ac.uk/pdbsum/1qfp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1qfp ProSAT]</span></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1qfp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qfp OCA], [https://pdbe.org/1qfp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1qfp RCSB], [https://www.ebi.ac.uk/pdbsum/1qfp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1qfp ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/SN_MOUSE SN_MOUSE]] Acts as an endocytic receptor mediating clathrin dependent endocytosis. Macrophage-restricted adhesion molecule that mediates sialic-acid dependent binding to lymphocytes, including granulocytes, monocytes, natural killer cells, B-cells and CD8 T-cells (By similarity). Preferentially binds to alpha-2,3-linked sialic acid. Binds to SPN/CD43 on T-cells. May play a role in hematopoiesis. May act as a counter-receptor for CLEC10A in lymph node.<ref>PMID:15364954</ref>
[https://www.uniprot.org/uniprot/SN_MOUSE SN_MOUSE] Acts as an endocytic receptor mediating clathrin dependent endocytosis. Macrophage-restricted adhesion molecule that mediates sialic-acid dependent binding to lymphocytes, including granulocytes, monocytes, natural killer cells, B-cells and CD8 T-cells (By similarity). Preferentially binds to alpha-2,3-linked sialic acid. Binds to SPN/CD43 on T-cells. May play a role in hematopoiesis. May act as a counter-receptor for CLEC10A in lymph node.<ref>PMID:15364954</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Lk3 transgenic mice]]
[[Category: Mus musculus]]
[[Category: Burtnick, L]]
[[Category: Burtnick L]]
[[Category: Crocker, P R]]
[[Category: Crocker PR]]
[[Category: Jones, E Y]]
[[Category: Jones EY]]
[[Category: May, A P]]
[[Category: May AP]]
[[Category: Robinson, R C]]
[[Category: Robinson RC]]
[[Category: Carbohydrate binding]]
[[Category: Immunoglobulin]]
[[Category: Immunoglobulin superfamily]]

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