1ci5: Difference between revisions
No edit summary |
No edit summary |
||
Line 1: | Line 1: | ||
==GLYCAN-FREE MUTANT ADHESION DOMAIN OF HUMAN CD58 (LFA-3)== | ==GLYCAN-FREE MUTANT ADHESION DOMAIN OF HUMAN CD58 (LFA-3)== | ||
<StructureSection load='1ci5' size='340' side='right'caption='[[1ci5 | <StructureSection load='1ci5' size='340' side='right'caption='[[1ci5]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1ci5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[1ci5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CI5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1CI5 FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ci5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ci5 OCA], [https://pdbe.org/1ci5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ci5 RCSB], [https://www.ebi.ac.uk/pdbsum/1ci5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ci5 ProSAT]</span></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ci5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ci5 OCA], [https://pdbe.org/1ci5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ci5 RCSB], [https://www.ebi.ac.uk/pdbsum/1ci5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ci5 ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/LFA3_HUMAN LFA3_HUMAN] Ligand of the T-lymphocyte CD2 glycoprotein. This interaction is important in mediating thymocyte interactions with thymic epithelial cells, antigen-independent and -dependent interactions of T-lymphocytes with target cells and antigen-presenting cells and the T-lymphocyte rosetting with erythrocytes. In addition, the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells. | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Line 31: | Line 32: | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Dotsch | [[Category: Dotsch V]] | ||
[[Category: Kim | [[Category: Kim M]] | ||
[[Category: Li | [[Category: Li J]] | ||
[[Category: Reinherz | [[Category: Reinherz EL]] | ||
[[Category: Sun | [[Category: Sun ZYJ]] | ||
[[Category: Wagner | [[Category: Wagner G]] | ||