4bpl: Difference between revisions

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<StructureSection load='4bpl' size='340' side='right'caption='[[4bpl]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
<StructureSection load='4bpl' size='340' side='right'caption='[[4bpl]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4bpl]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Orysa Orysa] and [https://en.wikipedia.org/wiki/Xenopus Xenopus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BPL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4BPL FirstGlance]. <br>
<table><tr><td colspan='2'>[[4bpl]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Oryza_sativa Oryza sativa] and [https://en.wikipedia.org/wiki/Xenopus Xenopus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BPL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4BPL FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[4bqk|4bqk]]</div></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4bpl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bpl OCA], [https://pdbe.org/4bpl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4bpl RCSB], [https://www.ebi.ac.uk/pdbsum/4bpl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4bpl ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4bpl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bpl OCA], [https://pdbe.org/4bpl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4bpl RCSB], [https://www.ebi.ac.uk/pdbsum/4bpl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4bpl ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/IMA1A_ORYSJ IMA1A_ORYSJ]] Functions in nuclear protein import. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Promotes docking of import substrates to the nuclear envelope.<ref>PMID:9727027</ref> <ref>PMID:11124253</ref>
[https://www.uniprot.org/uniprot/IMA1A_ORYSJ IMA1A_ORYSJ] Functions in nuclear protein import. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Promotes docking of import substrates to the nuclear envelope.<ref>PMID:9727027</ref> <ref>PMID:11124253</ref>  


==See Also==
==See Also==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Orysa]]
[[Category: Oryza sativa]]
[[Category: Xenopus]]
[[Category: Xenopus]]
[[Category: Chang, C W]]
[[Category: Chang C-W]]
[[Category: Counago, R M]]
[[Category: Counago RM]]
[[Category: Kobe, B]]
[[Category: Kobe B]]
[[Category: Williams, S J]]
[[Category: Williams SJ]]
[[Category: Nuclear import]]
[[Category: Nuclear localization signal]]
[[Category: Transport protein]]

Latest revision as of 14:56, 20 December 2023

rice importin_alpha in complex with nucleoplasmin NLSrice importin_alpha in complex with nucleoplasmin NLS

Structural highlights

4bpl is a 2 chain structure with sequence from Oryza sativa and Xenopus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.3Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

IMA1A_ORYSJ Functions in nuclear protein import. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Promotes docking of import substrates to the nuclear envelope.[1] [2]

See Also

References

  1. ↑ Jiang CJ, Imamoto N, Matsuki R, Yoneda Y, Yamamoto N. Functional characterization of a plant importin alpha homologue. Nuclear localization signal (NLS)-selective binding and mediation of nuclear import of nls proteins in vitro. J Biol Chem. 1998 Sep 11;273(37):24083-7. PMID:9727027
  2. ↑ Jiang CJ, Shoji K, Matsuki R, Baba A, Inagaki N, Ban H, Iwasaki T, Imamoto N, Yoneda Y, Deng XW, Yamamoto N. Molecular cloning of a novel importin alpha homologue from rice, by which constitutive photomorphogenic 1 (COP1) nuclear localization signal (NLS)-protein is preferentially nuclear imported. J Biol Chem. 2001 Mar 23;276(12):9322-9. Epub 2000 Dec 20. PMID:11124253 doi:http://dx.doi.org/10.1074/jbc.M006430200

4bpl, resolution 2.30Å

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