4an1: Difference between revisions

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<StructureSection load='4an1' size='340' side='right'caption='[[4an1]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
<StructureSection load='4an1' size='340' side='right'caption='[[4an1]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4an1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pig Pig]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AN1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4AN1 FirstGlance]. <br>
<table><tr><td colspan='2'>[[4an1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AN1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4AN1 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2P8:(2S)-N-BENZYL-2-({(2S)-2-[(1R)-1,2-DIHYDROXYETHYL]PYRROLIDIN-1-YL}CARBONYL)PYRROLIDINE-1-CARBOXAMIDE'>2P8</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1e5t|1e5t]], [[1e8m|1e8m]], [[1e8n|1e8n]], [[1h2w|1h2w]], [[1h2x|1h2x]], [[1h2y|1h2y]], [[1h2z|1h2z]], [[1o6f|1o6f]], [[1o6g|1o6g]], [[1qfm|1qfm]], [[1qfs|1qfs]], [[1uoo|1uoo]], [[1uop|1uop]], [[1uoq|1uoq]], [[1vz2|1vz2]], [[1vz3|1vz3]], [[2xdw|2xdw]], [[4amy|4amy]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2P8:(2S)-N-BENZYL-2-({(2S)-2-[(1R)-1,2-DIHYDROXYETHYL]PYRROLIDIN-1-YL}CARBONYL)PYRROLIDINE-1-CARBOXAMIDE'>2P8</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Prolyl_oligopeptidase Prolyl oligopeptidase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.26 3.4.21.26] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4an1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4an1 OCA], [https://pdbe.org/4an1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4an1 RCSB], [https://www.ebi.ac.uk/pdbsum/4an1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4an1 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4an1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4an1 OCA], [https://pdbe.org/4an1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4an1 RCSB], [https://www.ebi.ac.uk/pdbsum/4an1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4an1 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/PPCE_PIG PPCE_PIG]] Cleaves peptide bonds on the C-terminal side of prolyl residues within peptides that are up to approximately 30 amino acids long.  
[https://www.uniprot.org/uniprot/PPCE_PIG PPCE_PIG] Cleaves peptide bonds on the C-terminal side of prolyl residues within peptides that are up to approximately 30 amino acids long.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Pig]]
[[Category: Sus scrofa]]
[[Category: Prolyl oligopeptidase]]
[[Category: Bunker A]]
[[Category: Bunker, A]]
[[Category: Canning P]]
[[Category: Canning, P]]
[[Category: Danne R]]
[[Category: Danne, R]]
[[Category: Fulop V]]
[[Category: Fulop, V]]
[[Category: Garcia-Horsman A]]
[[Category: Garcia-Horsman, A]]
[[Category: Hokkanen J]]
[[Category: Hokkanen, J]]
[[Category: Juhasz T]]
[[Category: Juhasz, T]]
[[Category: Karttunen M]]
[[Category: Karttunen, M]]
[[Category: Kaszuba K]]
[[Category: Kaszuba, K]]
[[Category: Mannisto PT]]
[[Category: Mannisto, P T]]
[[Category: Rog T]]
[[Category: Rog, T]]
[[Category: St-Pierre JF]]
[[Category: St-Pierre, J F]]
[[Category: Szeltner Z]]
[[Category: Szeltner, Z]]
[[Category: Alpha/beta-hydrolase]]
[[Category: Amnesia]]
[[Category: Beta-propeller]]
[[Category: Hydrolase]]

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