2xxx: Difference between revisions

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<StructureSection load='2xxx' size='340' side='right'caption='[[2xxx]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
<StructureSection load='2xxx' size='340' side='right'caption='[[2xxx]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2xxx]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XXX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XXX FirstGlance]. <br>
<table><tr><td colspan='2'>[[2xxx]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XXX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XXX FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GLU:GLUTAMIC+ACID'>GLU</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.098&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2i0c|2i0c]], [[1tt1|1tt1]], [[1s7y|1s7y]], [[1yae|1yae]], [[2i0b|2i0b]], [[1s9t|1s9t]], [[2xxr|2xxr]], [[1s50|1s50]], [[1sd3|1sd3]], [[2xxv|2xxv]], [[2xxt|2xxt]], [[2xxu|2xxu]], [[2xxy|2xxy]], [[2xxw|2xxw]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GLU:GLUTAMIC+ACID'>GLU</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xxx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xxx OCA], [https://pdbe.org/2xxx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xxx RCSB], [https://www.ebi.ac.uk/pdbsum/2xxx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xxx ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xxx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xxx OCA], [https://pdbe.org/2xxx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xxx RCSB], [https://www.ebi.ac.uk/pdbsum/2xxx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xxx ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/GRIK2_RAT GRIK2_RAT]] Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. May be involved in the transmission of light information from the retina to the hypothalamus. Modulates cell surface expression of NETO2 (By similarity).<ref>PMID:17486098</ref> <ref>PMID:17115050</ref>
[https://www.uniprot.org/uniprot/GRIK2_RAT GRIK2_RAT] Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. May be involved in the transmission of light information from the retina to the hypothalamus. Modulates cell surface expression of NETO2 (By similarity).<ref>PMID:17486098</ref> <ref>PMID:17115050</ref>  
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<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Buffalo rat]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Green, T]]
[[Category: Rattus norvegicus]]
[[Category: Mayans, O]]
[[Category: Green T]]
[[Category: Nayeem, N]]
[[Category: Mayans O]]
[[Category: Transport protein]]
[[Category: Nayeem N]]

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