2xd7: Difference between revisions

<table><tr><td colspan='2'>[[2xd7]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XD7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XD7 FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.09&#8491;</td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xd7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xd7 OCA], [https://pdbe.org/2xd7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xd7 RCSB], [https://www.ebi.ac.uk/pdbsum/2xd7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xd7 ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/H2AW_HUMAN H2AW_HUMAN] Variant histone H2A which replaces conventional H2A in a subset of nucleosomes where it represses transcription. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in stable X chromosome inactivation.<ref>PMID:15621527</ref>  

[[Category: Homo sapiens]]

[[Category: Arrowsmith CH]]

[[Category: Bountra C]]

[[Category: Carpenter EP]]

[[Category: Edwards A]]

[[Category: Gileadi O]]

[[Category: Krojer T]]

[[Category: Muniz JRC]]

[[Category: Phillips C]]

[[Category: Ugochukwu E]]

[[Category: Vollmar M]]

[[Category: Weigelt J]]

[[Category: Von Delft F]]