2x7b: Difference between revisions
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<StructureSection load='2x7b' size='340' side='right'caption='[[2x7b]], [[Resolution|resolution]] 1.95Å' scene=''> | <StructureSection load='2x7b' size='340' side='right'caption='[[2x7b]], [[Resolution|resolution]] 1.95Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2x7b]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[2x7b]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharolobus_solfataricus_P2 Saccharolobus solfataricus P2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X7B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2X7B FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=COA:COENZYME+A'>COA</scene></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=COA:COENZYME+A'>COA</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2x7b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2x7b OCA], [https://pdbe.org/2x7b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2x7b RCSB], [https://www.ebi.ac.uk/pdbsum/2x7b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2x7b ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2x7b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2x7b OCA], [https://pdbe.org/2x7b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2x7b RCSB], [https://www.ebi.ac.uk/pdbsum/2x7b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2x7b ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/NAT_SACS2 NAT_SACS2] Displays alpha (N-terminal) acetyltransferase activity. Catalyzes the covalent attachment of an acetyl moiety from acetyl-CoA to the free alpha-amino group at the N-terminus of a protein (PubMed:17511810, PubMed:23959863, PubMed:25728374). NAT is able to acetylate the alpha-amino group of methionine, alanine and serine N-terminal residue substrates, however it has a preference for Ser-N-terminal substrates (PubMed:17511810, PubMed:23959863, PubMed:25728374).<ref>PMID:17511810</ref> <ref>PMID:23959863</ref> <ref>PMID:25728374</ref> | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: | [[Category: Saccharolobus solfataricus P2]] | ||
[[Category: Carter | [[Category: Carter LG]] | ||
[[Category: Johnson | [[Category: Johnson KA]] | ||
[[Category: Liu | [[Category: Liu H]] | ||
[[Category: Mackay | [[Category: Mackay D]] | ||
[[Category: Mcmahon | [[Category: Mcmahon SA]] | ||
[[Category: Naismith | [[Category: Naismith JH]] | ||
[[Category: Oke | [[Category: Oke M]] | ||
[[Category: Taylor | [[Category: Taylor GL]] | ||
[[Category: White | [[Category: White MF]] | ||