2wjp: Difference between revisions

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<StructureSection load='2wjp' size='340' side='right'caption='[[2wjp]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
<StructureSection load='2wjp' size='340' side='right'caption='[[2wjp]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2wjp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_dh5[alpha] Escherichia coli dh5[alpha]]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WJP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WJP FirstGlance]. <br>
<table><tr><td colspan='2'>[[2wjp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_DH5alpha Escherichia coli DH5alpha]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WJP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WJP FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AZI:AZIDE+ION'>AZI</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=D17:N-({3-[({4-[(Z)-(4-OXO-2-THIOXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]PHENYL}AMINO)METHYL]PHENYL}CARBONYL)-L-GLUTAMIC+ACID'>D17</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=KCX:LYSINE+NZ-CARBOXYLIC+ACID'>KCX</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AZI:AZIDE+ION'>AZI</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=D17:N-({3-[({4-[(Z)-(4-OXO-2-THIOXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]PHENYL}AMINO)METHYL]PHENYL}CARBONYL)-L-GLUTAMIC+ACID'>D17</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=KCX:LYSINE+NZ-CARBOXYLIC+ACID'>KCX</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2vtd|2vtd]], [[2uuo|2uuo]], [[2jfg|2jfg]], [[1uag|1uag]], [[4uag|4uag]], [[2uag|2uag]], [[2jfh|2jfh]], [[3uag|3uag]], [[2uup|2uup]], [[1e0d|1e0d]], [[2vte|2vte]], [[2jff|2jff]], [[1eeh|1eeh]]</div></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/UDP-N-acetylmuramoyl-L-alanine--D-glutamate_ligase UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.2.9 6.3.2.9] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wjp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wjp OCA], [https://pdbe.org/2wjp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wjp RCSB], [https://www.ebi.ac.uk/pdbsum/2wjp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wjp ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wjp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wjp OCA], [https://pdbe.org/2wjp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wjp RCSB], [https://www.ebi.ac.uk/pdbsum/2wjp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wjp ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/MURD_ECOLI MURD_ECOLI]] Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).[HAMAP-Rule:MF_00639]  
[https://www.uniprot.org/uniprot/MURD_ECOLI MURD_ECOLI] Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).[HAMAP-Rule:MF_00639]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase]]
[[Category: Blanot D]]
[[Category: Blanot, D]]
[[Category: Contreras-Martel C]]
[[Category: Contreras-Martel, C]]
[[Category: Dessen A]]
[[Category: Dessen, A]]
[[Category: Gobec S]]
[[Category: Gobec, S]]
[[Category: Kikelj D]]
[[Category: Kikelj, D]]
[[Category: Kovac A]]
[[Category: Kovac, A]]
[[Category: Muller-Premru M]]
[[Category: Muller-Premru, M]]
[[Category: Peterlin-Masic L]]
[[Category: Peterlin-Masic, L]]
[[Category: Rupnik V]]
[[Category: Rupnik, V]]
[[Category: Sink R]]
[[Category: Sink, R]]
[[Category: Tomasic T]]
[[Category: Tomasic, T]]
[[Category: Turk S]]
[[Category: Turk, S]]
[[Category: Zega A]]
[[Category: Zega, A]]
[[Category: Zidar N]]
[[Category: Zidar, N]]
[[Category: Cell cycle]]
[[Category: Cell division]]
[[Category: Cell shape synthesis]]
[[Category: Cell wall biogenesis/degradation]]
[[Category: Ligase]]
[[Category: Peptidoglycan synthesis]]

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