2w9c: Difference between revisions
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<StructureSection load='2w9c' size='340' side='right'caption='[[2w9c]], [[Resolution|resolution]] 2.90Å' scene=''> | <StructureSection load='2w9c' size='340' side='right'caption='[[2w9c]], [[Resolution|resolution]] 2.90Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2w9c]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[2w9c]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharolobus_solfataricus_P2 Saccharolobus solfataricus P2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W9C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2W9C FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DOC:2,3-DIDEOXYCYTIDINE-5-MONOPHOSPHATE'>DOC</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=O2G:2-DEOXY-N,N-DIMETHYL-5-O-[OXIDO(OXO)PHOSPHONIO]GUANOSINE'>O2G</scene>, <scene name='pdbligand=TTP:THYMIDINE-5-TRIPHOSPHATE'>TTP</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2w9c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w9c OCA], [https://pdbe.org/2w9c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2w9c RCSB], [https://www.ebi.ac.uk/pdbsum/2w9c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2w9c ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2w9c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w9c OCA], [https://pdbe.org/2w9c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2w9c RCSB], [https://www.ebi.ac.uk/pdbsum/2w9c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2w9c ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/DPO4_SACS2 DPO4_SACS2] Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. It is involved in translesional synthesis. | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</div> | </div> | ||
<div class="pdbe-citations 2w9c" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 2w9c" style="background-color:#fffaf0;"></div> | ||
==See Also== | |||
*[[DNA polymerase 3D structures|DNA polymerase 3D structures]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: | [[Category: Saccharolobus solfataricus P2]] | ||
[[Category: Egli | [[Category: Egli M]] | ||
[[Category: Eoff | [[Category: Eoff RL]] | ||
[[Category: Guengerich | [[Category: Guengerich FP]] | ||
[[Category: Kosekov | [[Category: Kosekov ID]] | ||
[[Category: Rizzo | [[Category: Rizzo CJ]] | ||
[[Category: Zhang | [[Category: Zhang H]] | ||