2vxt: Difference between revisions

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<StructureSection load='2vxt' size='340' side='right'caption='[[2vxt]], [[Resolution|resolution]] 1.49&Aring;' scene=''>
<StructureSection load='2vxt' size='340' side='right'caption='[[2vxt]], [[Resolution|resolution]] 1.49&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2vxt]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human] and [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VXT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VXT FirstGlance]. <br>
<table><tr><td colspan='2'>[[2vxt]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VXT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VXT FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.49&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1j0s|1j0s]], [[2vxu|2vxu]], [[2vxv|2vxv]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vxt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vxt OCA], [https://pdbe.org/2vxt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vxt RCSB], [https://www.ebi.ac.uk/pdbsum/2vxt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vxt ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vxt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vxt OCA], [https://pdbe.org/2vxt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vxt RCSB], [https://www.ebi.ac.uk/pdbsum/2vxt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vxt ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/IL18_HUMAN IL18_HUMAN]] Augments natural killer cell activity in spleen cells and stimulates interferon gamma production in T-helper type I cells.  
[https://www.uniprot.org/uniprot/IL18_HUMAN IL18_HUMAN] Augments natural killer cell activity in spleen cells and stimulates interferon gamma production in T-helper type I cells.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Lk3 transgenic mice]]
[[Category: Mus musculus]]
[[Category: Argiriadi, M A]]
[[Category: Argiriadi MA]]
[[Category: Borhani, D W]]
[[Category: Borhani DW]]
[[Category: Ghayur, T]]
[[Category: Ghayur T]]
[[Category: Wu, C]]
[[Category: Wu C]]
[[Category: Xiang, T]]
[[Category: Xiang T]]
[[Category: Autoimmunity]]
[[Category: Cytokine]]
[[Category: Fab]]
[[Category: Glycoprotein]]
[[Category: Il-18]]
[[Category: Immunoglobulin domain]]
[[Category: Immunoglobulin v region]]
[[Category: Secreted]]
[[Category: Th1/th2 cell]]

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