2bo7: Difference between revisions

<table><tr><td colspan='2'>[[2bo7]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Rhodothermus_marinus Rhodothermus marinus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BO7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BO7 FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.95&#8491;</td></tr>

<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2bo7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bo7 OCA], [https://pdbe.org/2bo7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2bo7 RCSB], [https://www.ebi.ac.uk/pdbsum/2bo7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2bo7 ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/MGS_RHOMR MGS_RHOMR] Involved in the biosynthesis of the stress protectant 2-O-alpha-D-mannosyl glycerate (MG) which is produced in response to growth at supraoptimal temperature and salinity, and protects several enzymes against inactivation by temperature, freeze-drying and osmotic stress. Catalyzes the condensation of alpha-GDP-D-mannose (GDP-Man) with D-glycerate to produce alpha-mannosyl-D-glycerate. It is specific for GDP-Man, but it can also use alpha-GDP-D-glucose (GDP-Glc), beta-GDP-D-fuctose, alpha-UDP-D-mannose and alpha-UDP-D-glucose as sugar donors. It is specific for D-glycerate, but it can also use D-lactate and glycolate as sugar acceptors. This reaction occurs with a net retention of anomeric configuration; the newly formed glycosidic linkage has the same alpha configuration as the sugar donor.<ref>PMID:10585410</ref> <ref>PMID:15951819</ref> <ref>PMID:21288903</ref>  

[[Category: Bolam DN]]

[[Category: Davies GJ]]

[[Category: Davis BG]]

[[Category: Dodson EJ]]

[[Category: Flint J]]

[[Category: Gilbert HJ]]

[[Category: Martinez-Fleites C]]

[[Category: Tailford LE]]

[[Category: Taylor E]]

[[Category: Yang M]]