1usx: Difference between revisions
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<StructureSection load='1usx' size='340' side='right'caption='[[1usx]], [[Resolution|resolution]] 2.70Å' scene=''> | <StructureSection load='1usx' size='340' side='right'caption='[[1usx]], [[Resolution|resolution]] 2.70Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1usx]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[1usx]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Avian_orthoavulavirus_1 Avian orthoavulavirus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1USX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1USX FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DAN:2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC+ACID'>DAN</scene>, <scene name='pdbligand=SIA:O-SIALIC+ACID'>SIA</scene>, <scene name='pdbligand=WIA:METHYL(6S)-1-THIO-L-MANNO-HEXODIALDO-6,2-PYRANOSIDE'>WIA</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1usx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1usx OCA], [https://pdbe.org/1usx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1usx RCSB], [https://www.ebi.ac.uk/pdbsum/1usx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1usx ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1usx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1usx OCA], [https://pdbe.org/1usx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1usx RCSB], [https://www.ebi.ac.uk/pdbsum/1usx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1usx ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/HN_NDVB HN_NDVB] Attaches the virus to sialic acid-containing cell receptors and thereby initiating infection. Binding of HN protein to the receptor induces a conformational change that allows the F protein to trigger virion/cell membranes fusion (By similarity). Neuraminidase activity ensures the efficient spread of the virus by dissociating the mature virions from the neuraminic acid containing glycoproteins (By similarity). | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Avian orthoavulavirus 1]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Groves D]] | |||
[[Category: Groves | [[Category: Itzstein M]] | ||
[[Category: Itzstein | [[Category: Kiefel M]] | ||
[[Category: Kiefel | [[Category: Portner A]] | ||
[[Category: Portner | [[Category: Takimoto T]] | ||
[[Category: Takimoto | [[Category: Taylor G]] | ||
[[Category: Taylor | [[Category: Zaitsev V]] | ||
[[Category: Zaitsev | |||