1gl1: Difference between revisions

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<StructureSection load='1gl1' size='340' side='right'caption='[[1gl1]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
<StructureSection load='1gl1' size='340' side='right'caption='[[1gl1]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1gl1]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GL1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1GL1 FirstGlance]. <br>
<table><tr><td colspan='2'>[[1gl1]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus] and [https://en.wikipedia.org/wiki/Locusta_migratoria Locusta migratoria]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GL1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1GL1 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1ab9|1ab9]], [[1acb|1acb]], [[1afq|1afq]], [[1ca0|1ca0]], [[1cbw|1cbw]], [[1cgi|1cgi]], [[1cgj|1cgj]], [[1chg|1chg]], [[1dlk|1dlk]], [[1ex3|1ex3]], [[1gcd|1gcd]], [[1gct|1gct]], [[1gg6|1gg6]], [[1ggd|1ggd]], [[1gha|1gha]], [[1ghb|1ghb]], [[1gl0|1gl0]], [[1gmc|1gmc]], [[1gmd|1gmd]], [[1gmh|1gmh]], [[1hja|1hja]], [[1mtn|1mtn]], [[1pmc|1pmc]], [[1vgc|1vgc]], [[2cga|2cga]], [[2gch|2gch]], [[2gct|2gct]], [[2gmt|2gmt]], [[2vgc|2vgc]], [[3gch|3gch]], [[3gct|3gct]], [[3vgc|3vgc]], [[4gch|4gch]], [[4vgc|4vgc]], [[5gch|5gch]], [[6gch|6gch]], [[7gch|7gch]], [[8gch|8gch]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Chymotrypsin Chymotrypsin], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.1 3.4.21.1] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1gl1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gl1 OCA], [https://pdbe.org/1gl1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1gl1 RCSB], [https://www.ebi.ac.uk/pdbsum/1gl1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1gl1 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1gl1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gl1 OCA], [https://pdbe.org/1gl1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1gl1 RCSB], [https://www.ebi.ac.uk/pdbsum/1gl1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1gl1 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/LCM_LOCMI LCM_LOCMI]] Both LCMI I and II are inhibitors of chymotrypsin and elastase (in vitro). They both inhibit the prophenol oxidase activation cascade.
[https://www.uniprot.org/uniprot/CTRA_BOVIN CTRA_BOVIN]  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Bos taurus]]
[[Category: Bos taurus]]
[[Category: Chymotrypsin]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Kellenberger, C]]
[[Category: Locusta migratoria]]
[[Category: Roussel, A]]
[[Category: Kellenberger C]]
[[Category: Hydrolase]]
[[Category: Roussel A]]
[[Category: Hydrolase-inhibitor complex]]
[[Category: Hydrolase/inhibitor]]
[[Category: Serine protease]]
[[Category: Serine protease inhibitor]]

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