1e3o: Difference between revisions
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<StructureSection load='1e3o' size='340' side='right'caption='[[1e3o]], [[Resolution|resolution]] 1.90Å' scene=''> | <StructureSection load='1e3o' size='340' side='right'caption='[[1e3o]], [[Resolution|resolution]] 1.90Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1e3o]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[1e3o]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1E3O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1E3O FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1e3o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1e3o OCA], [https://pdbe.org/1e3o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1e3o RCSB], [https://www.ebi.ac.uk/pdbsum/1e3o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1e3o ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1e3o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1e3o OCA], [https://pdbe.org/1e3o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1e3o RCSB], [https://www.ebi.ac.uk/pdbsum/1e3o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1e3o ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/PO2F1_HUMAN PO2F1_HUMAN] Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. Modulates transcription transactivation by NR3C1, AR and PGR (By similarity). In case of human herpes simplex virus (HSV) infection, POU2F1 forms a multiprotein-DNA complex with the viral transactivator protein VP16 and HCFC1 thereby enabling the transcription of the viral immediate early genes.<ref>PMID:1684878</ref> | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Pohl | [[Category: Pohl E]] | ||
[[Category: Remenyi | [[Category: Remenyi A]] | ||
[[Category: Schoeler | [[Category: Schoeler H]] | ||
[[Category: Tomilin | [[Category: Tomilin A]] | ||
[[Category: Wilmanns | [[Category: Wilmanns M]] | ||