1wqe: Difference between revisions
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==An unusual fold for potassium channel blockers: NMR structure of three toxins from the scorpion Opisthacanthus madagascariensis== | ==An unusual fold for potassium channel blockers: NMR structure of three toxins from the scorpion Opisthacanthus madagascariensis== | ||
<StructureSection load='1wqe' size='340' side='right'caption='[[1wqe | <StructureSection load='1wqe' size='340' side='right'caption='[[1wqe]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1wqe]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Opisthacanthus_madagascariensis Opisthacanthus madagascariensis]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WQE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WQE FirstGlance]. <br> | <table><tr><td colspan='2'>[[1wqe]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Opisthacanthus_madagascariensis Opisthacanthus madagascariensis]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WQE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WQE FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wqe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wqe OCA], [https://pdbe.org/1wqe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wqe RCSB], [https://www.ebi.ac.uk/pdbsum/1wqe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wqe ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wqe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wqe OCA], [https://pdbe.org/1wqe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wqe RCSB], [https://www.ebi.ac.uk/pdbsum/1wqe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wqe ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/KKX23_OPIMA KKX23_OPIMA] Decreases the amplitude of the potassium current of the rat channels Kv1.1/KCNA1 by 33% and Kv1.2/KCNA2 by 8% as well as human Kv1.3/KCNA3 by 70%.<ref>PMID:15631621</ref> | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Opisthacanthus madagascariensis]] | [[Category: Opisthacanthus madagascariensis]] | ||
[[Category: Chagot | [[Category: Chagot B]] | ||
[[Category: Corzo | [[Category: Corzo G]] | ||
[[Category: Dai | [[Category: Dai L]] | ||
[[Category: Darbon | [[Category: Darbon H]] | ||
[[Category: Ferrat | [[Category: Ferrat G]] | ||
[[Category: Nakajima | [[Category: Nakajima T]] | ||
[[Category: Pil | [[Category: Pil J]] | ||
[[Category: Pimentel | [[Category: Pimentel C]] | ||
[[Category: Tytgat | [[Category: Tytgat J]] | ||