7fi6: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[7fi6]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7FI6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7FI6 FirstGlance]. <br> | <table><tr><td colspan='2'>[[7fi6]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7FI6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7FI6 FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7fi6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7fi6 OCA], [https://pdbe.org/7fi6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7fi6 RCSB], [https://www.ebi.ac.uk/pdbsum/7fi6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7fi6 ProSAT]</span></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7fi6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7fi6 OCA], [https://pdbe.org/7fi6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7fi6 RCSB], [https://www.ebi.ac.uk/pdbsum/7fi6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7fi6 ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/NKG2D_HUMAN NKG2D_HUMAN] Receptor for MICA, MICB, ULBP1, ULBP2, ULBP3 (ULBP2>ULBP1>ULBP3) and ULBP4. Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. Involved in the immune surveillance exerted by T- and B-lymphocytes. | |||
==See Also== | |||
*[[NK cell receptor|NK cell receptor]] | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
Latest revision as of 20:16, 29 November 2023
Crystal structure of human MICA mutants in complex with natural killer cell receptor NKG2DCrystal structure of human MICA mutants in complex with natural killer cell receptor NKG2D
Structural highlights
FunctionNKG2D_HUMAN Receptor for MICA, MICB, ULBP1, ULBP2, ULBP3 (ULBP2>ULBP1>ULBP3) and ULBP4. Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. Involved in the immune surveillance exerted by T- and B-lymphocytes. See Also |
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