7few: Difference between revisions

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[7few]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7FEW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7FEW FirstGlance]. <br>
<table><tr><td colspan='2'>[[7few]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7FEW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7FEW FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CMP:ADENOSINE-3,5-CYCLIC-MONOPHOSPHATE'>CMP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CMP:ADENOSINE-3,5-CYCLIC-MONOPHOSPHATE'>CMP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7few FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7few OCA], [https://pdbe.org/7few PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7few RCSB], [https://www.ebi.ac.uk/pdbsum/7few PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7few ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7few FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7few OCA], [https://pdbe.org/7few PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7few RCSB], [https://www.ebi.ac.uk/pdbsum/7few PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7few ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/VFR_PSEAE VFR_PSEAE]] Can bind cyclic AMP. Is a global regulator of virulence factor expression and is required for exotoxin A and protease production.
[https://www.uniprot.org/uniprot/VFR_PSEAE VFR_PSEAE] Can bind cyclic AMP. Is a global regulator of virulence factor expression and is required for exotoxin A and protease production.
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</StructureSection>
</StructureSection>

Revision as of 20:14, 29 November 2023

Pseudomonas aeruginosa Virulence Factor Regulator with cAMP ligand and auranofin gold analoguesPseudomonas aeruginosa Virulence Factor Regulator with cAMP ligand and auranofin gold analogues

Structural highlights

7few is a 2 chain structure with sequence from Pseudomonas aeruginosa PAO1. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.75Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

VFR_PSEAE Can bind cyclic AMP. Is a global regulator of virulence factor expression and is required for exotoxin A and protease production.

7few, resolution 1.75Å

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OCA